The link between total antioxidant status, total oxidant status, arylesterase activity, and subgingival microbiota in psoriasis patients
Yükleniyor...
Dosyalar
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background Studies focusing on the relationship between periodontitis and systemic diseases have suggested a possible association between these two chronic and inflammatory disorders. We aimed to comparatively investigate the salivary oxidative status, biomarker levels, clinical findings, and the microbial load on subgingival biofilm samples in psoriasis patients and controls. Methods Forty participants were allocated into four groups as follows: (1) systemically and periodontally healthy (C group); (2) systemically healthy with periodontitis (P group); (3) psoriasis (Ps) and periodontally healthy (Ps-C group); and (4) Ps with periodontitis (Ps-P group). Subgingival biofilm samples were obtained to detect the periodontopathogenic agents by Real-time PCR (qPCR). The total antioxidant status (TAS) (mmol/l), total oxidant status (TOS) (mu mol/l), and arylesterase (ARE) activity (U/L) were analyzed using saliva samples. Results The level of TOS and oxidative stress index (OSI) were significantly higher in patients with Ps-P and P compared to controls (P = 0.001, and P < 0.001, respectively). ARE levels were higher in controls compared to Ps and P (P < 0.001). The prevalences of bacteria detected in subgingival biofilm samples were similar between all groups (P > 0.05). Conclusions This study reported that psoriasis may amplify TOS and OSI, and the co-existence of psoriasis and periodontitis may aggravate oxidative stress.
Açıklama
Anahtar Kelimeler
Chronic Plaque Psoriasis, Peri-Implant Diseases, 2017 World Workshop, Oxidative Stress, Chronic Periodontitis;, Consensus Report
Kaynak
International Journal of Dermatology
WoS Q Değeri
Q1
Scopus Q Değeri
Q2
Cilt
61
Sayı
12
Künye
Paksoy, T., Ustaoğlu, G., Yaman, D., Arıöz, Ö., Demirci, M., Ünlü, Ö., ... & Polat, M. (2022). The link between total antioxidant status, total oxidant status, arylesterase activity, and subgingival microbiota in psoriasis patients.
