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Öğe The use of low level laser therapy in conjunction with diode laser-assisted and conventional vestibuloplasty: Comparison of wound healing and vestibular depth gain(Elsevier, 2023) Karaş, Mert; Günpınar, ŞadiyeBackground: The aim of this study is to compare wound healing and vestibular depth gain in individuals undergoing vestibule deepening surgery using diode laser and conventional technique and to further investigate the possible wound healing effect of low-level laser therapy (LLLT).Material and Methods: 52 systemically healthy individuals with insufficient vestibular depth in the region of teeth 33-43 in the lower jaw were included. Following nonsurgical periodontal treatment, patients were divided into four groups as follows: a) diode laser (L); b) diode laser + LLLT; c) conventional surgery and d) conventional surgery + LLLT. Vestibular depth and horizontal wound size measurements of the individuals were recorded using digital calipers. Reepithelization was evaluated via an image analysis program.Results: Vestibular depth measurements were found to be higher in the conventional surgery groups compared to that of diode laser groups after the operation, while the results were not statistically different between groups (p >0.05). Reepithelization area did not differ between groups in the evaluated time periods (p >0,05). On the other hand, horizontal wound shrinkage was significantly higher in the conventional surgery group than that of diode laser.Conclusions: Within the limits of this study, both methods yielded in vestibule depth gain. On the other hand, LLLT did not have an additional positive effect on mucosal wound healing. As a clinical relevance, the results are valuable for clinicians in terms of showing that suturing of the mucosal flap formed following vestibule deepening should not be necessary in laser assisted surgery for attaining more vestibule depth.(c) 2023 Elsevier Masson SAS. All rights reserved.Öğe Applying nano-HA in addition to scaling and root planing increases clinical attachment gain(The Korean Academy of Periodontology, 2022) Uysal, Özge; Ustaoğlu, Gülbahar; Behçet, Mustafa; Albayrak, Önder; Tunalı, MustafaPurpose: This study evaluated the efficacy of treating periodontitis using subgingival nano-hydroxyapatite powder with an air abrasion device (NHAPA) combined with scaling and root planing (SRP). Methods: A total of 28 patients with stage III periodontitis (grade B) were included in this study, although 1 was lost during follow-up and 3 used antibiotics. The patients were divided into a test group and a control group. All patients first received whole-mouth SRP using hand instruments, and a split-mouth approach was used for the second treatment. In the test group, the teeth were treated with NHAPA for 15 seconds at 70% power per pocket. Subgingival plaque samples were obtained from the 2 deepest pockets at the test and control sites before treatment (baseline) and 3 months after treatment. The full-mouth plaque index (PI), gingival index (GI), papillary bleeding index (PRI), bleeding on probing (BOP), probing depth (PD) and clinical attachment level (CAL) were recorded at baseline and at 1- and 3-month post-treatment. Real-time polymerase chain reaction was used to determine the colonisation of Treponema denticola (Td), Porphyromonas,gingivalis(Pg), and Aggrega Odder actinomycelemcomitans in the subgingival plaque. Results: From baseline to the first month, the test group showed significantly larger changes in BOP and CAL (43.705%+/- 27.495% and 1.160 +/- 0.747 mm, respectively) than the control group (36.311%+/- 27.599% and 0.947 +/- 0.635 mm, respectively). Periodontal parameters had improved in both groups at 3 months. The reductions of PI, GI, BOP, PD, and CAL in the test group at 3 months were greater and statistically significant. The total bacterial count and Td and Pg species had decreased significantly by the third month in both groups (P<0.05). Conclusions: Applying NHAPA in addition to SRP improves clinical periodontal parameters more than SRP alone. Subgingival NHAPA may encourage clot adhesion to tooth surfaces by increasing surface wettability.Öğe Evaluation of the knowledge level, behavior, and attitudes of obstetrics and gynecology specialists on the relationship between periodontal diseases and pregnancy outcomes(Galenos Publishing House, 2022) Ustaoğlu, Gülbahar; Ural, Ülkü Mete; Paksoy, Tuğçe; Ankaralı, HandanObjective: To investigate the knowledge and awareness level of obstetricians on the relationship between periodontal diseases (PDs) and adverse pregnancy outcomes, and to compare them regarding gender, age, professional experience and institution to identify the pertaining issues requiring improvement. Materials and Methods: Data were collected by the administration of an online questionnaire. The link was sent to the e-mail addresses of 80 obstetricians (50 female, 30 men). The questionnaire consisted of 23 questions focused on the determination of the personal characteristics, attitudes, and the level of knowledge of obstetricians about the relationship between periodontal diseases and preterm labor. Results: The presence of gingival disease (GD) was higher in females (p=0.001). Females were found to be more aware and sensitive about the relationship between the periodontal diseases and poor obstetric outcomes (p<0.05). Obstetricians in training and research institutions and obstetricians in the early postgraduate period were more likely to believe that there was a significant relationship between GD and obstetric outcomes (p<0.05). Conclusion: The knowledge and awareness level of obstetricians on the relationship between PDs and adverse pregnancy outcomes may be influenced by gender, age, professional experience and institution. Active collaboration between periodontologists and obstetricians will provide benefits in monitoring and follow-up of the oral health of pregnant women in terms of prevention of poor obstetric outcomes.Öğe CBCT image artefacts generated by implants located inside the field of view or in the exomass(British Institute of Radiology, 2022) Kocasaraç, Hüsniye Demirtürk; Koenig, Lisa J.; Ustaoğlu, Gülbahar; Oliveira, Matheus Lima; Freitas, Deborah QueirozObjectives: To compare artefacts in cone-beam computed tomography (CBCT) arising from implants of different materials located either inside the field of view (FOV) or in the exomass, and to test different image-acquisition parameters to reduce them. Methods: CBCT scans of a human mandible prepared with either a titanium, titanium-zirconium, or zirconia implant were acquired with the Planmeca ProMax utilizing FOV sizes of 8 x 5 cm and 4 x 5 cm, which placed the implant inside the FOV (8 x 5 cm) or in the exomass (4 x 5 cm). The scanning parameters considered three conditions of metal artefact reduction (MAR), disabled, low, and high, and 2 kVp levels (80 and 90). The standard deviation (SD) of grey values of regions of interest was obtained. The effects of implant material, implant position, MAR condition, kVp level, and their interactions were evaluated by Analysis of Variance (alpha = 5%). Results: The zirconia implant produced the highest SD values (more heterogeneous grey values, corresponding to greater artefact expression), followed by titanium-zirconium, and titanium. In general, implants in the exomass produced images with higher SD values than implants inside the FOV. MAR was effective in decreasing SD values, especially from the zirconia implant, only when the implant was inside the FOV. Images with 80 kVp had higher SD values than those with 90 kVp, regardless of the other factors (p < 0.05). Conclusions: Implants in the exomass lead to greater artefact expression than when they are inside the FOV. Special attention should be paid to scanning parameters that reduce metal-related artefacts, such as MAR activation and increasing kVp. This is especially important with a zirconia implant inside the FOV.Öğe Evaluation of bacterial colonization and clinical properties of different suture materials in dentoalveoler surgery(W B Saunders Co-Elseiver Inc, 2022) Yaman, Deniz; Paksoy, Tuğçe; Ustaoğlu, Gülbahar; Demirci, MehmetPurpose: This study aimed to compare the effects of 10 different suture materials commonly used in dentoalveolar surgery on wound healing, their postoperative microbial colonization, and related clinical parameters. Methods: A total of 172 suture samples from patients who had undergone extraction of impacted third molars were included in the study. The suture materials studied were poly-glycolide-colactide, fast absorbable poly-glycolide-colactide, poly-glycolic acid-cocaprolactone, polydioxanone, silk, polypropylene, polyvinylidene difluoride, polyamide, polyester, and polytetrafluoroethylene (PTFE). The microbial colonization in all sutures and clinical parameters were evaluated after 1 week. Results: Multifilament sutures had higher bacterial colonization compared with monofilament sutures (P < .001). No dental plaque accumulation was observed in any samples of polypropylene sutures. Polydioxanone, PTFE, and poly-glycolic acid-cocaprolactone sutures exhibited less postoperative slack compared with all other sutures after 1 week. Patients with silk, polyvinylidene difluoride, and PTFE sutures had less suture-related discomfort. According to the Landry index score, monofilament sutures demonstrated superior wound healing to multifilament sutures (P = .019). In addition, nonabsorbable sutures showed significantly better wound epithelization than absorbable sutures (P < .001). Conclusions: Bacterial colonization and tissue reactions due to the surface properties of the suture affected the wound healing after dentoalveolar surgery. Multifilament sutures should not be applied for prolonged periods because of their tendency for microbial colonization. The tissue reaction to the absorbable suture materials may adversely affect wound healing. (C) 2021 The American Association of Oral and Maxillofacial Surgeons.Öğe Is online video a suitable source to obtain sufficient and useful information about peri-implantitis?(W B Saunders Co-Elseiver Inc, 2023) Bulut, Duygu Göller; Paksoy, Tuğçe; Ustaoğlu, GülbaharPurpose: Recently, with the increase in cases of peri-implantitis, the amount of data patients can receive via social media about the condition has increased. The study presented here aims to examine what online videos (YouTubeTM, Google LLC, San Bruno, California) offer patients about peri-implantitis and to evaluate the quality of the information presented.Materials and Methods: In this cross-sectional study, a systematic search was conducted into online videos containing information about peri-implantitis using the keyword peri-implantitis by an experienced periodontologist. The source of videos, video type, duration, number of days since upload, number of views, comments, likes, dislikes, and interaction index of each video were recorded. Videos were scored according to content; Score 0 (low content): videos with no description of clinical presentations, risk factors, or management options; Score 1 (moderate content): videos that described 1 clinical presentation and 1 etiologic factor and did not describe management options; Score 2 (high content): videos with the description of at least 2 clinical presentations, 2 etiologic factors, and 1 management option. The quality of each video was evaluated using the Global Quality Scale and DISCERN. Data were analyzed using the Kruskal-Wallis test, Spearman's test, and multinomial logistic regression analysis. Intraobserver agreement was calculated as the intraclass correlation coefficient.Results: The first 200 videos were screened and, after exclusions, 103 videos were included for further analysis. United States-based videos were the majority (14 videos), 46.6% of the videos were uploaded by healthcare professionals, and 99% were in the educational videos category. Video content score 2 videos have higher mean values with 4,871.945 views, 6.002 comments, 50.729 likes, 7.751 viewing rate, and 0.023 interaction index than score 0 videos (P < .05). Statistically significant positive correlations were found between the video content score, Global Quality Scale, DISCERN, and the data showing the popularity and visibility of the videos (P < .01).Conclusions: Overall, half of the top-ranked online videos are valuable sources of information about peri-implantitis. Videos with high content are more popular and are of greater quality than videos with low content.(c) 2022 American Association of Oral and Maxillofacial SurgeonsJ Oral Maxillofac Surg 81:56-64, 2023Öğe The effects of vitamin D deficiency on mandibular bone structure: A retrospective radiological study(Springer, 2023) Korkmaz, Meltem Zihni; Yemenoğlu, Hatice; Günaçar, Dilara Nil; Ustaoğlu, Gülbahar; Yıldırım, Esra AteşObjective The aim of the study was to evaluate the effects of vitamin D deficiency on the mandibular bone structure by fractal analysis and panoramic morphometric indices. Methods Ninety participants were divided into three groups as 30 individuals with severe vitamin D deficiency, 30 individuals with vitamin D deficiency, and 30 individuals with vitamin D sufficiency. Fractal dimension analysis (FD), panoramic mandibular index (PMI), mandibular cortical index (MCI), and mandibular cortical thickness measurement (CTM) were evaluated on panoramic radiographs. Results FD values of the patients with vitamin D deficiency were found to be statistically lower than the patients with vitamin D sufficiency (p < 0.05). FD value of supracortical area above the angulus mandible (FD2) in patients with severe vitamin D deficiency was significantly lower than FD values (p = 0.002). There was no statistically significant difference between the groups in the CTM (p > 0.05). PMI was significantly lower in patients with severe vitamin D deficiency (p < 0.001). There was a significant difference in MCI values between the groups (p < 0.05). Conclusion Vitamin D deficiency causes a decrease in bone mineral density in the mandible, and an increase in alveolar porosity. FD analysis and radiomorphometric indices in panoramic radiographs can be used to assess osteoporotic changes in patients with vitamin D deficiency.Öğe In vivo evaluation of mandibular trabecular and cortical bone quality in psoriasis vulgaris(ELSEVIER SCIENCE INC, 2022) Günaçar, Dilara Nil; Bulut, Duygu Göller; Ustaoğlu, Gülbahar; Yıldırım, Esra AteşObjective. The aim of this study was to evaluate the effects of psoriasis vulgaris on mandibular structure by calculating fractal dimension (FD) and radiomorphometric indices. Study Design. Panoramic radiographs of 58 patients with psoriasis and 58 healthy participants were assessed. FD was used to analyze trabecular bone architecture in the condyle, angle, and 2 sites in the alveolar bone. Five radiomorphometric indices based on cortical thickness and the mandibular cortical index (MCI) for structure were used to assess cortical bone porosity. Comparisons were made between sites in trabecular and cortical bone. Quantitative and categorical data were statistically analyzed with the significance level at P < .05. Results. FD was significantly lower in the patients with psoriasis than in the controls in the alveolar bone sites (P <= .035). Differences between measurement sites were insignificant in psoriasis (P >= .617), but the FD values of some measurement sides in the control group differed significantly (P <= .004). All quantitative radiomorphometric indices were significantly lower in patients with psoriasis (P <= .034) with significant differences between some sites in both groups. No significant difference was found in MG frequency distribution between the groups (P = .782). Conclusions. Trabecular architecture and cortical thickness were negatively affected in patients with psoriasis, but no differences in cortical porosity were detected between groups.Öğe Effects of hyperlipidemia on trabecular and cortical structures of the mandible(British Inst Radiology, 2022) Günaçar, Dilara Nil; Yemenoğlu, Hatice; Ustaoğlu, Gülbahar; Arıöz, ÖzkanObjectives: To evaluate the mandibular bone structure of patients with hyperlipidemia by fractal dimension (FD) analysis and panoramic radiomorphometric indices including mandibular cortical thickness measurement, panoramic mandibular index (PMI), mandibular cortical index (MCI) and to compare with the healthy group. Methods: In total, 60 panoramic radiographs were included, including panoramic radiographs of 30 individuals with hyperlipidemia and 30 individuals with systemically healthy. FD analysis in the mandibular condyle, angle of the mandible, the distal side of the second premolar and anterior to mental foramen, PMI, MCI, and mandibular cortical thickness measurements were evaluated on radiographs. Independent samples t-test was used for differences between healthy and hyperlipidemia groups with regard to age and PMI. Repeated measurement of variance with one within and one between factors in the comparison of four regions and two groups in terms of FD and cortical thickness measurements. Following this analysis, significant differences were detected by post-hoc Sidak test. Fisher-Freeman-Halton analysis was applied to determine the relationship between categorical variables. Results: FD values of the hyperlipidemic patients were found to be lower than the healthy group. Between the hyperlipidemic and healthy groups, there was a difference in the angle of the mandible FD values (p = 0.020). There were no differences in the cortical thickness measurements and PMI between the groups (p > 0.05). There was a difference in MCI values between the groups (p < 0.05). Conclusion: The trabecular structure of the angle of the mandible and the cortical bone structure of the mandible were found to be negatively affected by hyperlipidemia.Öğe The link between total antioxidant status, total oxidant status, arylesterase activity, and subgingival microbiota in psoriasis patients(Wiley, 2022) Paksoy, Tuğçe; Ustaoğlu, Gülbahar; Yaman, Deniz; Arıöz, Özkan; Demirci, Mehmet; Polat, MuallaBackground Studies focusing on the relationship between periodontitis and systemic diseases have suggested a possible association between these two chronic and inflammatory disorders. We aimed to comparatively investigate the salivary oxidative status, biomarker levels, clinical findings, and the microbial load on subgingival biofilm samples in psoriasis patients and controls. Methods Forty participants were allocated into four groups as follows: (1) systemically and periodontally healthy (C group); (2) systemically healthy with periodontitis (P group); (3) psoriasis (Ps) and periodontally healthy (Ps-C group); and (4) Ps with periodontitis (Ps-P group). Subgingival biofilm samples were obtained to detect the periodontopathogenic agents by Real-time PCR (qPCR). The total antioxidant status (TAS) (mmol/l), total oxidant status (TOS) (mu mol/l), and arylesterase (ARE) activity (U/L) were analyzed using saliva samples. Results The level of TOS and oxidative stress index (OSI) were significantly higher in patients with Ps-P and P compared to controls (P = 0.001, and P < 0.001, respectively). ARE levels were higher in controls compared to Ps and P (P < 0.001). The prevalences of bacteria detected in subgingival biofilm samples were similar between all groups (P > 0.05). Conclusions This study reported that psoriasis may amplify TOS and OSI, and the co-existence of psoriasis and periodontitis may aggravate oxidative stress.Öğe The prevalence and correlates of fissured tongue among outpatients in Andkhoy city, Afghanistan: A cross-sectional study(Dove Medical Press Ltd, 2021) Hamrah, Mohammad Hassan; Baghalian, Ali; Ghadimi, Sara; Mokhtar, Saeedeh; Kargar, Mojgan; Dahi, TobaBackground: Fissured tongue is a common manifestation of the tongue, marked by the presence of multiple prominent grooves or fissures on the dorsal surface of the tongue. However, there is a lack of studies focusing on the prevalence and factors associated with fissured tongue among patients attending an outpatient clinic in Afghanistan. Aim: The purpose of the current study was to determine the prevalence and factors associated with fissured tongue and its effects on the general health of adult outpatients in Afghanistan. Patients and Methods: The cross-sectional survey was conducted among outpatient populations in Andkhoy City, Afghanistan, between September 2019 and December 2019. A convenience technique was applied by including 1182 patient aged 18-80 years. Socio-economic status, smoking, nass use (smokeless tobacco use) and medical data were collected using face-to-face interviews. We used logistic regression analysis to identify factors associated with fissured tongue. A convenience technique was applied by including patient aged 18-80 years. Results: The studied population consisted of 1182 participants, of whom 573 (48.5%) were males and 609 (51.5%) females. The prevalence of fissured tongue was 27.2% (95% CI: 24.7-29.9%) with males having significantly higher prevalence than females (47.5%, 95% CI: 43.3-51.6% versus 8.2%, 95% CI: 6.2-10.7%, p<0.001). Male participants (OR=7.1, 95% CI: 4.8-10.3), diabetes mellitus (OR=1.6, 95% CI: 1.1-2.3) and smokeless tobacco use (OR=12.0, 95% CI: 8.1-17.6) were the only variables independently associated with fissured tongue. Conclusion: This study suggested that there was a high rate of fissured tongue among an outpatient clinic in Andkhoy, Afghanistan. Male gender, diabetes mellitus, and nass consumption were associated with fissured tongue. Therefore, these factors might usefully be targeted in local health promotion, prevention and early intervention programs.Öğe A comparison of the autogenous bone collection capacity of two bur drill systems used in implant surgery with different bur diameters and lengths at different drilling speeds: an in vitro study(QUINTESSENCE PUBLISHING CO INC, 2021) Güler, Şeki; Bayrakdar, Sevda Kurt; Öğütücü, UmutPurpose: The aim of this study was to compare the bone collection capacity of bur drill systems used in implant surgery with different diameters, lengths, and drilling speeds. Materials and Methods: This study was performed on bovine ribs. Two bur drill systems were studied: Implantium (Dentium) and Straumann (Institut Straumann). The groups were divided into subgroups according to the bur diameter. As a result, there were four Implantium subgroups (3.3, 3.8, 4.3, and 4.8 mm) and three Straumann subgroups (3.3, 4.1, and 4.8 mm). In addition, for each bur diameter, the bone collection capacities of the drill systems were evaluated at three different drilling speeds (150, 250, and 400 rpm) and two bur lengths (10 and 12 mm). The diameter, length, and speed changes were performed, and the results were compared between the two drill systems. Results: The mean bone weight collected by using the Straumann burs was higher than that of the Implantium burs at each drilling speed and bur length. Using the Straumann system, the different drilling speeds/lengths of the burs had no impact on the bone collection capacity, irrespective of the bur diameter (P > .05). However, the drilling speeds/lengths of the Implantium system resulted in a statistically significant difference in the same diameters (P < .05). Conclusion: Both bur systems were suitable for autogenous graft collection for bone grafting in implant surgery, but the Straumann burs were more successful than the Implantium burs.Öğe Comparison of the effectiveness of Ankaferd Blood Stopper® and Emdogain in periodontal regeneration(Wiley, 2022) Güler, Şevki; Çetinkaya, Burcu Özkan; Bayrakdar, Sevda Kurt; Ayas, Bülent; Keleş, Gonca ÇayırObjectives The present study was performed to compare the effectiveness of Ankaferd Blood Stopper(R) (ABS) with enamel matrix derivatives (EMD) for treating fenestration defects in rats. Materials and Methods Forty-eight male Wistar rats were randomly divided into six groups (each n = 8). Fenestration defects were created in all rats, to which ABS, EMD, or saline (S) was then applied. The rats were grouped and sacrificed at one of two different time points, as follows: ABS-10-group, ABS-treatment/sacrifice on day 10; EMD-10-group, EMD-treatment/sacrifice on day 10; S-10-group, S-treatment/sacrifice on day 10; ABS-38-group, ABS-treatment/sacrifice on day 38; EMD-38-group, EMD-treatment/sacrifice on day 38; and S-38-group, S-treatment/sacrifice on day 38. Then, histomorphometric analysis including measurements of new bone area (NBA) and new bone ratio (NBR), and immunohistochemical analysis including the determination of osteopontin (OPN) and type-III-collagen (C-III) expression were performed. Results The NBA and NBR were significantly higher in the ABS-10-group and EMD-10-group compared to the S-10-group (p < .05), and in the EMD-38-group compared to the S-38-group (p < .05). The levels of C-III and OPN immunoreactivity were significantly higher in the ABS-10-group compared to the S-10-group (p < .017). Conclusions The results of this study suggested that ABS can promote early periodontal regeneration, although its efficacy seems to decrease over time.Öğe Dental and temporomandibular joint alterations in rheumatoid arthritis patients and their association with salivary oxidative stress(TUBITAK Scientific & Technical Research Council Turkey, 2021) Yaman, Deniz; Bulut, Duygu Göller; Ustaoğlu, Gülbahar; Avcı, Emre; Taşçı, MuratBackground/aim: Rheumatoid arthritis (RA) is the most extensive inflammatory arthritis causing permanent deformities in the joint. Increasing evidence suggests that oxidative stress is a substantial factor in the pathogenesis of RA. This study aimed to examine the salivary oxidant-antioxidant status of RA and control groups and to compare these biomarkers by correlating them with disease activity, acute phase reactants, and clinical findings. Materials and methods: Age and sex-matched 60 participants including 30 patients with RA and 30 control (50 females, 10 males; mean age: 42.62 +/- 10.89 years) were evaluated. RA disease activity and severity were evaluated by the disease activity score 28-C reactive protein (DAS 28-CRP). Rheumatoid factor (RF) positivity, anticitrullinated protein antibodies (ACPA) positivity, erythrocyte sedimentation rate (ESR), CRP, tender and swollen joint counts, and medical treatment regimens of the patients (glucocorticoids, conventional or biologic disease-modifying antirheumatic drugs) were recorded. In the radiographic examination, dental findings, and bone alterations of the temporomandibular joint (TMJ) were recorded and compared for both groups. Saliva samples were obtained for analysis of total antioxidant status (TAS), total oxidant status (TOS), arylesterase (ARE), and oxidative stress index (OSI) levels. The data analysis was conducted by independent sample t-test and chi-square test. Results: Condylar erosion was the most common radiographic change in TMJ of RA patients. Osteophyte formation was a prominent finding in the control group. Lower TAS and higher OSI levels were found in RA patients compared with controls (p = 0.013; p = 0.029, respectively). The effect of DAS 28-CRP score on the levels of oxidative stress biomarkers in RA patients was not significant. Conclusion: Oxidative stress causes tissue damage in response to excessive mechanical loading, which in turn promotes TMD. However, disease activity has not a prominent impact on the salivary oxidative stress status of RA patients.Öğe The effect of severe acute respiratory syndrome coronavirus 2 on the health of oral tissue: A survey-based study(Kerman University of Medical Sciences, 2021) Bulut, Duygu Göller; Türker, Nurşat; Serin, Sema; Ustaoğlu, GülbaharBACKGROUND AND AIM: The aim of this survey study was to determine the possible effects of coronavirus disease 2019 (COVID-19) on oral tissues and to investigate the relationship between changes in oral tissues and COVID-19. METHODS: In this study, 200 volunteers who had COVID-19 in their anamnesis were included. After the routine clinical examination in the Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Bolu Abant Izzet Baysal University, Bolu, Turkey, the volunteers were asked to fill out a 33-item questionnaire created on Google Forms to determine the changes occurred in the oral tissues during and after COVID-19. Data were analysed using descriptive statistics in SPSS software and the statistical significance level was determined using the chi-square test and McNemar's test. RESULTS: The study population consisted of 75 men and 125 women. While suffering from COVID-19, 53.0, 21.0, 16.0, and 17.5% of the subjects reported that they had taste loss, halitosis, pain in the chewing muscles, and pain in the temporomandibular joint (TMJ), respectively. Pain and wound in the oropharynx were the variables that more affected the possibility of halitosis (P < 0.001, Odds ratio = 4.749). Xerostomia was observed in 38.0% of the patients during the disease. In 27.6% of the patients who had xerostomia during the disease, the complaint associated with this complication continued after recovery (P < 0.001). CONCLUSION: Xerostomia and loss of taste were the most common symptoms in the oral area during COVID-19. Further studies including clinical studies are needed to determine the relationship between changes in oral tissues and COVID-19. the original work is properlyÖğe Periodontal health education session can improve oral hygiene in patients with gingivitis: A masked randomized controlled clinical study(Wiley, 2022) Gürpınar, Sadiye; Meracı, BilgeBackground The aim of this clinical trial was to evaluate the effect of a periodontal health education session (PHES), which included education on the pathogenesis and consequences of periodontal diseases on oral hygiene motivation in patients with gingivitis. Methods A randomized controlled clinical trial was conducted on 50 (26 females and 24 males) patients with gingivitis who underwent periodontal treatment. Subjects were randomly allocated into the PHES group (experimental group) and standard oral hygiene education group (control group). The Rustogi Modified Navy Plaque Index (RMNPI) and Papillary Bleeding Index (PBI) were used to evaluate oral hygiene at baseline and were repeated after 1, 3, and 6 months. Knowledge about periodontal disease was measured and the participants' motivation was determined using the Oral Hygiene Motivation Scale. Results Although baseline knowledge levels and motivation scores were not different between the groups, following the educational motivational interviewing (MI) session, levels were higher in the experimental compared with the control group. The subjects' RMNPI and PBI scores at the 1-, 3-, and 6- month re-examinations were statistically higher in the control group than the experimental group. Furthermore, the level of knowledge and intrinsic and total motivation scores were moderately positively correlated with a reduction in clinical indices at 6 months compared with baseline. Conclusions The results of this study indicated that increased knowledge and awareness about periodontal diseases and its consequences, including systemic effects, via educational MI session increased intrinsic motivation and improved oral hygiene of patients with gingivitis, especially regarding interproximal surfaces.Öğe Investigation of patients with coronary slow flow in terms of periodontal health status(Assoc Medica Brasileira, 2021) Erdal, Emrah; Ustaoğlu, Gülbahar; Karaş, Zeynep; Bilgin, SatılmışOBJECTIVE: This study aims to evaluate the relationship between periodontal health status and coronary slow flow phenomenon. METHODS: One hundred and two patients who underwent coronary angiography with the diagnosis of stable angina pectoris were included in the study. Patients were divided into two groups: patients with coronary slow flow (Test group) (n=51), and patients with normal coronary angiography (Control group) (n=51). Diagnosis of slow coronary flow was made according to Beltrame criteria by coronary angiography. Demographic characteristics of the participants were recorded. The periodontal health was assessed by clinical periodontal parameters such as probing depth, clinical attachment level, gingival index, plaque index, and bleeding on probing. RESULTS: There were no significant differences between groups as regards the frequencies of hypertension, smoking (p>0.05). As for the periodontal parameters of the study groups, probing depth, gingival index, plaque index, bleeding on probing, and clinical attachment level values were statistically higher in the test group compared to the control group (p<0.05). CONCLUSIONS: Periodontitis might be accepted as one of the underlying causes of coronary slow flow. Patients with coronary slow flow should be evaluated for an underlying periodontal disease, and treatment of periodontal disease can protect against future cardiovascular events.Öğe Evaluation of periodontal health in breast cancer patients undergoing tamoxifen or aromatase inhibitors drugs therapy: A cross-sectional study(Wiley, 2021) Ustaoğlu, Gülbahar; Bulut, Duygu Göller; Üyetürk, Ümmügül; Uysal, ÖzgeAim: To study the dental and periodontal status of women with breast cancer (BCa) having tamoxifen or aromatase inhibitors (AIs) treatment in comparison with control healthy women. Methods: Fifty-one women on tamoxifen therapy, 52 women on AIs therapy and 52 systemically healthy controls were included in the study. The total number of teeth, the number of teeth indicated for extraction, the number of decayed teeth, and the duration of medication were recorded. Periodontal status was evaluated with gingival index (GI); plaque index (PI); bleeding on probing (BOP); probing depth (PD) and clinical attachment loss (CAL). Results: The lowest number of teeth and decayed teeth was found in AIs users (P < .001 and P = .003 respectively). The highest CAL value was seen in AIs users (P = .042) whereas no significant difference was found between the groups in terms of PI, GI, and PD (P = .102, P = .233, and P = .306, respectively). Lower PI was observed in patients using AIs for less than 2 years (P = .048). Conclusions While tamoxifen did not affect the dental and periodontal condition, AIs medication adversely affected the dental and periodontal condition by more tooth loss and higher CAL.Öğe Netrin-1 and its receptor Unc5b as markers of periodontal disease(Wiley, 2020) Günpınar, Şadiye; Meracı, Bilge; Dündar, NiyaziObjectives The aim of this present study was to evaluate the levels of Netrin-1 and Unc5b in periodontal health and disease. Background Netrin-1, acting via its receptor UNC5b, regulates the inflammatory response and takes apart in bone destructive diseases. Methods Samples of gingival crevicular fluid (GCF), whole saliva, and serum were taken from systemically healthy, nonsmoking 20 periodontitis , 20 gingivitis patients, and 20 periodontally healthy subjects at baseline and 4 weeks after nonsurgical periodontal treatment (NSPT). Whole-mouth and site-specific clinical periodontal parameters were recorded. Netrin-1 and Unc5b levels were measured by enzyme-linked immunosorbent assay. Data were analyzed by nonparametric tests. Results Total amount of Netrin-1 in GCF was significantly higher in periodontitis than the others, and the levels were significantly reduced after NSPT. Salivary and serum concentrations of Netrin-1 were significantly different among the study groups (P = .000), and NSPT significantly increased the concentration levels of both salivary and serum Netrin-1 (P < .05). Healthy subjects had significantly lower GCF (P = .001) and conversely, higher salivary and serum levels of Unc5b than the other groups (P = .002). The GCF levels of Unc5b were significantly reduced (P < .01), and conversely, serum concentrations were significantly increased after NSPT (P < .05). GCF Netrin-1 and Unc5b total amounts were positively correlated with clinical parameters (P P < .05) whereas salivary Netrin-1 and Unc5b concentrations were negatively correlated with clinical parameters (P P < .05). Conclusions The results of this study indicate that Netrin-1 and its receptor Unc5b may have essential roles in periodontal inflammation and those can be assumed as useful therapeutic agent to control inflammation and periodontal breakdown.Öğe Effects of non-surgical periodontal therapy on inflammatory markers of psoriasis: A randomized controlled trial(Wiley, 2020) Yarkaç, Fatma Uçan; Oğrum, Atiye; Göktürk, ÖzgeAim The purpose of this randomized controlled clinical study was to evaluate the effect of non-surgical mechanical periodontal therapy on the inflammatory status and severity of psoriasis in subjects with psoriasis. Material and methods The study population consisted of 92 periodontitis patients with psoriasis vulgaris suffering from an untreated periodontal disease. Two randomized groups were formed from these patients: immediate periodontal therapy (test group, n = 46) and delayed periodontal therapy (control group, n = 46). Periodontal clinical measures, on salivary interleukin 2, interleukin 6 and secretory immunoglobulin A levels and the Psoriasis Area and Severity Index (PASI) scores were evaluated at baseline and on the 8th week in control and test groups. Results Eight weeks after completion of non-surgical periodontal therapy (test group) or initial examination (control group), a significant decrease was observed in interleukin 2, interleukin 6 level and in PASI score, whereas a significant increase was observed in secretory immunoglobulin A levels in the test group (p < .05). Conclusion Within the limits of this study, the results suggest that effective periodontal therapy improves the psoriasis condition in patients afflicted by both diseases.
