Association between omentin levels and insulin resistance in pregnancy

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dc.authorid0000-0002-3156-1076en_US
dc.authorid0000-0001-7306-5233en_US
dc.authorid0000-0002-5924-7476
dc.contributor.authorAktaş, Gülali
dc.contributor.authorAlçelik, Aytekin
dc.contributor.authorÖzlü, Tülay
dc.contributor.authorTosun, Mehmet
dc.contributor.authorTekçe, Buket Kın
dc.contributor.authorSavlı, Haluk
dc.contributor.authorTekçe, Hikmet
dc.date.accessioned2021-06-23T19:36:11Z
dc.date.available2021-06-23T19:36:11Z
dc.date.issued2014
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractAims: Omentin is a new adipokine secreted mainly from visceral adipose tissue. Serum omentin is found to be reduced in patients with impaired glucose tolerance, type 2 diabetes mellitus, obesity and insulin resistant states. Despite the fact that pregnancy is also characterized with hyperinsulinemia, literature is lacking about data of omentin levels and its association with insulin resistance in pregnant women. We aimed to evaluate the association of omentin levels and insulin resistance in pregnant women and to compare these levels with those of non-pregnant, nondiabetic women. Methods: Uncomplicated pregnant women who admit to our outpatient clinics for routine follow-up were included in the study group. Non-pregnant women without diabetes mellitus were served as control group. Fasting glucose, insulin, omentin levels and HOMA IR were recorded. SPSS 15.0 for Windows was used for statistical analysis. Results: There were 36 pregnant women in the study group and 37 healthy, non-pregnant women in the control group. Serum omentin and fasting glucose levels were significantly decreased and fasting insulin was significantly increased in the study group compared to control group. Conclusion: Omentin might be an indicator of insulin resistance in pregnant women. Larger prospective studies are needed to claim whether omentin can have a clinical use for diagnosis of gestational diabetes mellitus.en_US
dc.identifier.doi10.1055/s-0034-1370917
dc.identifier.endpage166en_US
dc.identifier.issn0947-7349
dc.identifier.issn1439-3646
dc.identifier.issue3en_US
dc.identifier.pmid24643693en_US
dc.identifier.scopus2-s2.0-84896469163en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage163en_US
dc.identifier.urihttps://doi.org/10.1055/s-0034-1370917
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7947
dc.identifier.volume122en_US
dc.identifier.wosWOS:000347403300239en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAktaş, Gülali
dc.institutionauthorAlçelik, Aytekin
dc.institutionauthorÖzlü, Tülay
dc.institutionauthorTosun, Mehmet
dc.institutionauthorTekçe, Buket Kın
dc.institutionauthorSavlı, Haluk
dc.institutionauthorTekçe, Hikmet
dc.language.isoenen_US
dc.publisherJohann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbhen_US
dc.relation.ispartofExperimental And Clinical Endocrinology & Diabetesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOmentinen_US
dc.subjectInsulin Resistanceen_US
dc.subjectPregnancyen_US
dc.titleAssociation between omentin levels and insulin resistance in pregnancyen_US
dc.typeArticleen_US

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