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https://hdl.handle.net/20.500.12491/164

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The evaluation of red cell distribution width in chronic hemodialysis patients
(Hindawi Ltd, 2014) Tekçe, Hikmet; Tekçe, Buket Kin; Aktaş, Gülali; Tanrısev, Mehmet; Şit, Mustafa
Background. Red cell distribution width (RDW) has been used as a marker of iron deficiency; however, it is accepted as a marker of cardiovascular survival. We aimed to study RDW levels in hemodialysis (HD) patients and the association between RDW and inflammatory, nutritional, and volume markers. Methods. We included 296 HD patients with sufficient iron storage and without anemia or hypervolemia. We grouped patients into four groups according to clinical parameters, albumin, and C-reactive protein (CRP). Results. The lowest RDW levels were found in group 1 (13.2%). Although RDW of group 2 was higher than that of group 1, it was still in normal range (14.7% versus 13.2%, P = 0.028). RDW levels of groups 3 (17.8%) and 4 (18.5%) were significantly higher than those of groups 1 and 2 and above normal range. A positive correlation was detected between RDW and HD duration, interdialytic weight gain (IDWG), serum phosphate, and CRP levels and a negative correlation was detected with serum albumin. HD duration, CRP, IDWG, and serum albumin have been found as independent predictors of RDW elevation. Conclusions. Results of the present study reflect adverse effects of inflammation, malnutrition, and excess IDWG on RDW elevation in an HD study cohort with sufficient iron storage and without anemia and hypervolemia.
Factors influencing the duration of urine leakage following percutaneous nephrolithotomy
(Hindawi Ltd, 2014) Üyetürk, Uğur; Gücük, Adnan; Kemahlı, Eray; Dağıstan, Emine; Yıldız, Mevlüt; Yılmaz, Burak; Metin, Ahmet
Purpose. The duration of urine leakage following the removal of the nephrostomy tube after percutaneous nephrolithotomy (PCNL) shows significant variations depending on the techniques used. We aimed to assess the factors likely to influence the duration of urine leakage. Material and Methods. In total, 103 patients who underwent PCNL were reviewed retrospectively. DUL was evaluated regarding patient characteristics, thickness of the access line, presence of hydronephrosis, and residual stones. Results. DUL was significantly prolonged in accordance with a decrease in the thickness of parenchyma tissue (R = -0.716, P < 0.001). DUL was prolonged as the degree of hydronephrosis (R = 0.526, P < 0.001) and the number of patients with residual stones (R = 0.273, P = 0.005) increased. Median DUL was significantly longer in patients with residual stones than those without residual stones (P = 0.002). In the receiving operating curve analysis, the optimum cut-off value of parenchymal thickness for hospitalization <= 12 h was 17.2mm (sensitivity, 90.2%; specificity, 69.4%; P = 0.001). Conclusions. We found that parenchymal thickness of the access line, hydronephrosis, and residual stones were the most influential factors determining DUL following PCNL, respectively.
A case of giant hepatic hydatid cyst infected with morganella morganii and the literature review
(Hindawi Ltd, 2012) Hakyemez, İsmail Necati; Şit, Mustafa; Aktaş, Gülali; Taş, Tekin; Mengeloğlu, Fırat Zafer; Küçükbayrak, Abdülkadir
Hydatid cyst disease is a common worldwide zoonosis. Most of the cysts are located in the liver. Abscess formation due to infection of the cyst is an important complication. M. morganii, a Gram-negative Bacillus, is a quite rare cause of liver abscess. A 77-year-old woman was admitted to hospital with complaints of fever, chills, nausea, vomiting, loss of appetite, and abdominal pain located in the right-upper quadrant. Her history was positive for hepatic hydatid cyst disease ten years ago. Physical examination revealed a painful mass filling the right-upper quadrant and extending down to umbilicus. Indirect hemagglutinin test for hydatid cyst was positive at a titer of 1/320. Giant liver abscess due to infected hydatid cyst was found in computed tomography scan. Surgeons performed cystectomy and cholecystectomy. Cefazoline, cefuroxime, and metronidazole were administered empirically, but all the three agents were replaced with intravenous ceftriaxone after M. morganii was isolated from the cultures of the abscess material. Clinical signs of the patient resolved at the second week of treatment, and she was discharged.
The transmission of Helicobacter pylori via exposure to common sources outweighs the person-to-person contact among spouses in developing countries
(Elsevier Science Inc, 2000) Akcan, Y.; Ersan, S.; Alper, Murat; Bıcık, Z.; Aytuğ, N.
Primary subcutaneous cyst hydatic disease in proximal thigh: An unusual localisation: A case report
(Bmc, 2003) Orhan, Zafer; Kara, Hasan; Tüzüner, Tolga; Şencan, İrfan; Alper, Murat
Background: Musculoskeletal hydatidosis is very rare and represents 1% - 5.4% of all cases of echinococcosis. On clinical basis, infection mimics a soft-tissue tumor, and the preoperative radiological diagnosis is very important to avoid biopsy. Case Presentation: We report an unusual case of primary subcutaneous hydatidosis in proximity to vastus lateralis muscle. It was diagnosed according to the computed tomography appearance, clinical and pathological findings. A 43 year old female patient was admitted with a history of pain at proximal thigh for the last 30 days. On physical examination, a mass which was 4 x 5 cm in diameter, painful and erythamatous, was palpated over greater trochanter. Sedimentation rate was 40 mm in the first hour. CT (Computed Tomography) scan demonstrated, a soft tissue mass with central cystic component in the subcutaneous tissue near vastus lateralis muscle. Histopathological examination of the specimen revealed a pericystic structure, which consisted of connective tissue and scattered hyaline cells showing a necrotic basophilic structure that resembled a cuticular membrane. Treatment with high dose albendazole was conducted for 4 weeks. Conclusions: This case illustrates that echinococcal disease should be considered in the differential diagnosis of every cystic mass in every anatomic location, especially when they occur in areas where the disease is endemic.
Proprioception after primary repair of the anterior cruciate ligament (vol 52, pg 1199, 2024)
(Sage Publications Inc, 2024) Çiçeklidağ, Murat; Kaya, İbrahim; Ayanoğlu, Tacettin; Ayaş, İnci Hazal; Özer, Mustafa; Ataoğlu, Muhammet Baybars; Kanatlı, Ulunay
Pellet injuries to the orbit reply
(Karger, 2010) Kükner, A. Şahap; Alagöz, G.
Port-wine stain, laser therapy and pregnancy: Risk factors for multiple pyogenic granulomas?
(Blackwell Publishing, 2007) Kavak, Ayşe; Alper, Murat; Aydogan, İ.
Pyogenic granuloma (PG) and port-wine stain (PWS) are an acquired vascular tumour and a congenital malformation, respectively. A 35-year-old woman presented at 8 months’ gestation with a 1-month history of enlarging masses on the congenital lesion of the face. A congenital purple macular lesion limited to the right side of the face was found to be consistent with PWS. In addition, four red papules 26 mm in diameter were localized to PWS areas excluding normal skin (fig. 1). Spontaneous or post-traumatic bleeding history was denied. There was no oral or nasal lesion. Neurological and ophthalmological examinations were all normal. The patient had undergone five sessions of laser therapy 6 years earlier. She denied similar lesions during her first pregnancy 9 years ago.
Efficacy and pain tolerance of alexandrite laser hair removal at different stages of the menstrual cycle
(Oxford Univ Press Inc, 2024) Karanfil, Ertuğrul; Görgü, Metin
Background Several different parameters play a role in the transition of hair follicles to the anagen phase, with the role of androgens, progesterone, and estrogen hormones and receptors being significant.Objectives The effectiveness of laser hair removal (LHR) and pain tolerance during procedure were investigated during 3 different phases of the menstrual cycle.Methods Forty-eight axillae were randomly divided into 3 groups: menstruation, ovulation, and luteal. Three laser sessions were performed on each axilla at a 1-month interval. Blood hormone levels were measured in the patients. An alexandrite laser was applied during LHR sessions. Before each LHR session and 1 month after the third session, hair follicles in 4-cm2 areas in the center of the axillae were counted. Patients self-assessed the pain they felt during the laser application in each session with a visual pain scale.Results The average values for hair counting in the groups were as follows (M, menstruation; O, ovulation; L, luteinization): M0 = 47.6, M1 = 27.4, M2 = 16.1, M3 = 9.9; O0 = 41.8, O1 = 21.1, O2 = 13.8, O3 = 8.6; and L0 = 49.4, L1 = 27.1, L2 = 15.1, L3 = 9.8. The average values on the visual analog scale scores in the groups were: M1 = 3.94, M2 = 3.06, M3 = 1.94; O1 = 3.50, O2 = 3.06, O3 = 1.69; and L1 = 3.63, L2 = 2.50, L3 = 1.56. Statistical analysis was conducted with Tukey post hoc analysis after analysis of variance.Conclusions The results of LHR are not affected by changes in hormone levels during the menstrual cycle in females. Although not statistically significant, it has been observed that pain tolerance during laser application is lower during the menstruation cycle.
Effect of fasting on choroidal thickness and its diurnal variation
(Taylor & Francis Inc, 2019) Uyar, Enes; Doğan, Ümit; Ulaş, Fatih
Purpose: The aim of this study was to assess the effect of Ramadan fasting on choroidal thickness (CT) and its associated diurnal variations using spectral domain optic coherence tomography. Materials and Methods: Ocular measurements were performed on a single eye of 87 healthy individuals. Eyes were evaluated twice a day around 8.00 a.m. and 4.00 p.m. during Ramadan. Evaluations were repeated at the same time of the day, 1 month following Ramadan on the same subjects. Measurements of choroidal and retinal thickness were performed at central, temporal and nasal segments. Results: The comparison of measurements revealed that temporal CT at 8.00 a.m. and foveal, temporal and nasal CTs at 4.00 p.m. were significantly reduced during fasting (p values were 0.005, <0.001, 0.001 and 0.046, respectively). Mean changes of CTs during fasting were 14.76 ± 16.01, 9.90 ± 19.57 and 8.10 ± 16.81 µm at the fovea, temporal and nasal segments, respectively. However, CTs at non-fasting conditions were measured as 6.13 ± 12.93, 3.78 ± 15.23 and 5.05 ± 13.60 µm, respectively. In comparison, diurnal variations of foveal and temporal CTs during fasting were significantly higher than the controls (p values were <0.001 and 0.004, respectively). Additionally, retinal thicknesses during fasting were significantly reduced compared to the controls in all segments measured at 4.00 p.m. (p for all values <0.05) Conclusions: The results of the present study revealed that fasting and dehydration caused a reduction of the choroidal and retinal thicknesses. Likewise, they are also responsible for the increased diurnal variation of CTs. Therefore, early hours of the day may be preferred to evaluate retinal and choroidal thicknesses during Ramadan to avoid the effects of dehydration on the measurement results
The effects of prophylactic calcium dobesilate in experimetal renal ischemia reperfusion injury
(Elsevier Science Bv, 2010) Akkoç, Ali; Metin, A.; Kandıralı, E.; Eroğlu, M.; Yanık, S.; Özcan, F.
Endoscopic removal of obstructing sutures using argon plasma coagulation
(Mosby-Elsevier, 2014) Kolb, Jennifer M.; Kaltenbach, Tonya; Soetikno, Roy; Ghevariya, Vishal; Çöl, Cavit; Yılmaz, Bülent; Posul, Emrah
We present two unusual cases of persistent dysphagia, months after Ivor Lewis esophagectomy for esophageal adenocarcinoma, caused by retained sutures and staples blocking the passageway of food and fluid through the esophagus. We demonstrate the use of argon plasma coagulation (APC) at 30-W forced coagulation at 1 L/min to completely remove the PDS sutures from the esophagus with minimal damage to the underlying mucosa. We use the smaller diameter 4.5 fr catheter for precise APC application, using small bursts to melt the suture and staples. This method is safe and effective and can be performed by any endoscopist trained to use APC. After removing the obstructing sutures, we proceeded with balloon dilation of the narrowed anastomosis. Suture removal with APC treatment and subsequent stricture dilation led to significant improvement in symptoms and quality of life.
A new computer-associated occupational skin disorder: Mousing callus
(Mosby, Inc, 2006) Göksügür, Nadir; Çakıcı, Hüsamettin
Computer-associated disorders have become more common as more people use computers for extended periods, either for fun or work. We would like to report a new computer-related occupational dermatosis that we have named “mousing callus,” which results from friction and pressure on the hand secondary to computer mouse use. We recently saw a 35-year-old man who presented with a 2- × 1-cm yellowish, painless thickening on the palmar side of the wrist of his right hand (Fig 1). He also had mild, intermittent wrist pain when working. He was an academician who had spent 3 years using a mouse on average of approximately 10 hours a day. The patient used the computer mouse with his right hand in such a way that the affected part of the wrist made contact with his table. Seemingly, recurrent friction and pressure between the wrist and the table led to the evolution of his callus. When the arm and hand rest on a table in the anatomic position, pressure on the bony prominence of the carpal bone, the pisiform prominence, can induce trauma in the overlying skin
Vitamin B12 and recurrent aphthous stomatitis
(W B Saunders Co-Elsevier Inc, 2007) Köybaşı, Serap; Serin, Erdinç
The letter raises two points about a previous study that investigated possible etiological factors of recurrent aphthous stomatitis (RAS), including vitamin B12 deficiency. First, the letter questions whether the vitamin B12 and hematological results of the study are reliable, as 35% of subjects were B12 deficient but mean hemoglobin and hematocrit levels did not indicate anemia. Second, the letter asks why mean corpuscular volume, an important indicator for B12 deficiency, was not reported. The authors of the original study respond that their laboratory tests and results are reliable, vitamin B12 levels were not low enough to cause anemia, and they purposely did not report mean corpuscular volume to avoid confusing readers
The effect of amyloride and procaine on expression of heat shock protein 70 in rat retina
(Assoc Research Vision Ophthalmology Inc, 2002) Tunç, M.; Güven, A.; Cam, M.; Kaya, M.; Aktan, G.; Ziyal, İ
To identify the effects of amyloride and procaine in retinal expression of heat shock protein 70 (HSP 70) following traumatic injury. Methods: We induced traumatic stress by performing experimental spinal injury in 36 male Wistar-albino rats. We randomised the animals into three groups. Group I received no medications, Group II received intraperitoneal (IP) Procaine 15mg/kg, Group III received Amyloride 30 mg/kg IP. We sacrificed half of the animals in each groups at 12th hour and the remaining half in 24 hours. Following immidiate enucleation we isolated the retinae and detected HSP 70 immunoreactivity in each group. Results: There was moderate expression of HSP 70 in the outer nuclear and inner plexiform layer of the retinae after 12 hours and marked staining with HSP 70 antibodies 24 hours after the injury in all subjects which did not receive any medication. There was little or no immunoreaction to HSP 70 in rat retinae which received procaine or amyloride. Conclusion: Decreased expression of HSP 70 in the retina by procaine and amyloride indicates their neuroprotective role following traumatic stress.
Carcinoma of the gastric stump following billroth ii operation
(Oxford Univ Press, 2011) Çöl, Cavit; Hasdemir, Oğuz; Büyükaşık, Oktay
Impaired subjective sleep quality in irritable bowel syndrome patients with a type D personality
(Cambridge Univ Press, 2013) Yıldırım, Osman; Alçelik, Aytekin; Canan, Fatih; Aktaş, Gülali; Şit, Mustafa; İşçi, Ahsen; Yalçın, Abdullah
The importance of primary surgery in patients with de novo stage IV BC surviving at least 5 years: Protocol MF07-01 randomized clinical trial
(Oxford Univ Press, 2019) Özmen, V.; Özbaş, S.; Karanlık, H.; Müslümanoğlu, M.; Iğcı, A.; Cantürk, Z.; Utkan, Z.
The MF07-01 trial is a multicenter randomized study comparing locoregional treatment (LRT) followed by systemic therapy (ST) with ST alone in de novo stage IV breast cancer (BC) patients. The aim of this study is to evaluate the importance of LRT in patients who lived at least 5 years after the diagnosis of de novo Stage IV BC
Topical vancomycin is more efficient than povidone-ıodine treatment in controlling bacterial growth in methicillin-resistant staphylococcus aureus keratitis model in rabbits
(Taylor & Francis Inc, 2024) Alkan, Yunus; Kaymaz, Abdulgani; Behçet, Mustafa; Bayrak, Abdullah
Purpose: To evaluate the efficacy of topical vancomycin and povidone iodine (PI) application on methicillin-resistant Staphylococcus aureus (MRSA) keratitis model in rabbits. Methods: MRSA keratitis was induced by injecting 0.1 mL MRSA containing 1000 colony-forming units (CFU) into central cornea of right eyes of 24 New Zealand White rabbits. Animals were divided into four groups (n = 6): control (treated with balanced salt solution), 50 mg/mL topical vancomycin, 5% topical PI, and combination; examined before and after treatment, and corneal tissues were harvested for analysis at 9th hour of treatment. Results: Bacterial load was determined as: 7.63 +/- 0.82 log10 CFU/g in control group, 6.95 +/- 1.66 log10 CFU/g in PI group, 4.67 +/- 0.77 log10 CFU/g in combination group, and 4.33 +/- 0.71 log10 CFU/g in vancomycin group (p = 0.001). Median of total clinical score increased significantly from 7 [range: 5-8] to 11.5 [range: 11-15] (p = 0.001) in control group, did not change (6 [range: 5-8] to 7 [range: 5-7]; p = 0.695) in vancomycin group, increased significantly from 7 [range: 5-8] to 12.5 [range: 10-14] (p < 0.001) in PI group, increased significantly from 6.5 [range: 5-7] to 8 [range: 7-9] in combination group (p = 0.002). Post-treatment clinical scores for chemosis, conjunctival injection, iritis, hypopyon, epithelial erosion, and corneal infiltrate were significantly lower in vancomycin-treated groups compared to others (p < 0.05). In PI-treated groups, especially scores for chemosis, conjunctival injection, epithelial erosion and corneal infiltrate were significantly higher than vancomycin (p < 0.05). Conclusion: Topical vancomycin significantly inhibited bacterial growth in MRSA keratitis. However, PI was ineffective in controlling this growth; additionally, exerted toxic effect on ocular surface. When vancomycin was combined with PI, no additional increase in efficacy of treatment was detected compared to only vancomycin.
The combination of furosemide and intravenous hydration does not affect the success of shock wave lithotripsy in renal stone treatment: A prospective randomised single blinded trial
(Bmj Publishing Group, 2015) Kocaaslan, Ramazan; Küçükpolat, Salim; Karadağ, Mert Ali; Erkan, Erkan; Kadihasanoğlu, Mustafa; Özyalvaçlı, Mehmet Emin; Toktaş, Mahmut Gökhan
Objectives To investigate the effect of furosemide given before shock wave lithotripsy (SWL) in patients with renal stones. Methods Two-hundred patients with renal stones measuring 6-20mm in diameter were prospectively included in this study. The treatment group (n=100 patients) received 40mg furosemide 30min before SWL plus 1000mL 0.9% sodium chloride, infused during the procedure. Standard SWL alone was used for the control group (n=100 patients). The effectiveness of SWL was compared between the two groups. Results No statistically significant difference was found between the groups in age, stone size, Hounsfield units, urinary pH, stone density, average number of sessions, average number of pulses or mean energy used. The stone-free rate was 69% in the control group and 71% in the treatment group (p=0.758). Conclusions Although it is an easy and safe application, no positive effects of furosemide and hydration were found.

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