Multi-inflammatory index as a novel mortality predictor in critically Ill COVID-19 patients
Yükleniyor...
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Sage Publications Inc
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aim Systemic inflammation has a crucial role in the pathogenesis and mortality of Coronavirus disease 2019 (COVID-19). Multi-inflammatory index (MII) is a novel index related with systemic inflammation. In this study, we investigated the relationship between MII and in-hospital mortality in COVID-19 patients admitted to the intensive care unit (ICU). Methods We retrospectively analyzed the medical records of COVID-19 patients followed-up in the ICU of our institution between 01.04.2020 and 01.10.2021. Patients were classified into two groups according to mortality status as survivors and non-survivors. Various inflammatory parameters of the groups were compared and their efficacy in predicting mortality was investigated. Results Out of 348 study patients, 86 cases (24.7%) were in the survived group and 262 cases (75.3%) were in the dead group. The median age of the mortal group was significantly higher than that of the survived group (65.5 vs 76, P < .001). Multiple logistic regression analysis revealed that among all the included inflammatory parameters, MII showed the best efficacy for predicting mortality (OR: 0.999; 95% CI: 0.9991-0.9998; P = .003). Conclusion MII, a new combination of Neutrophil to lymphocyte ratio (NLR) and C-reactive protein (CRP), is a simple and practical biomarker that can help us in the prediction of mortality in COVID-19 patients followed-up in the ICU.
Açıklama
Anahtar Kelimeler
Coronavirus Disease 2019, Mortality, Intensive Care Unit, Multi-Inflammatory Index, Neutrophil
Kaynak
Journal of Intensive Care Medicine
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
37
Sayı
11
Künye
Gozdas, H. T., Kayis, S. A., Damarsoy, T., Ozsari, E., Turkoglu, M., Yildiz, I., & Demirhan, A. (2022). Multi-inflammatory index as a novel mortality predictor in critically Ill COVID-19 patients. Journal of Intensive Care Medicine, 37(11), 1480-1485.
