Comparison of GTR, T-PRF and open-flap debridement in the treatment of intrabony defects with endo-perio lesions: a randomized controlled trial

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dc.authorid0000-0002-4205-861X
dc.authorid0000-0002-1773-9114
dc.contributor.authorUstaoğlu, Gülbahar
dc.contributor.authorAydın, Zeliha Uğur
dc.contributor.authorÖzelçi, Ferhat
dc.date.accessioned2021-06-23T19:54:49Z
dc.date.available2021-06-23T19:54:49Z
dc.date.issued2020
dc.departmentBAİBÜ, Diş Hekimliği Fakültesi, Periodontoloji Ana Bilim Dalıen_US
dc.description.abstractBackground: Titanium-prepared platelet rich fibrin (T-PRF) is an autologous hemo-component with a high concentration of platelets that also incorporates leukocytes, and growth factors into the dense fibrin matrix and can be used as a healing biomaterial. This study assesses the adjunctive use of T-PRF in intrabony defects ( IBDs) with open flap debridement (OFD) in comparison with guided tissue regeneration (GTR) as a gold standard and OFD alone as a control. Material and Methods: A total of 45 patients (15 per group) were randomized as either T-PRF (test group), GTR (test group), or OFD alone (control group) sites. Probing depth (PD), clinical attachment level (CAL), and IBD were recorded. The radiographic depth of IBD was also measured. Primary outcomes assessed were changes in PD, CAL, and radiographic IBD that were assessed at the beginning and nine months later. Results: The PRF and GTR group showed significant improvement in clinical parameters compared with the OFD alone (control group) at nine months. While there were no significant differences in PD and CAL between test groups (T-PRF and GTR groups), the significant difference was found in radiographic IBD depth. Conclusion: T-PRF may give similar successful results as GTR in the treatment of IBDs with endo-perio lesions.en_US
dc.identifier.doi10.4317/medoral.23231
dc.identifier.endpageE123en_US
dc.identifier.issn1698-6946
dc.identifier.issue1en_US
dc.identifier.pmid31880284en_US
dc.identifier.scopus2-s2.0-85077345980en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpageE117en_US
dc.identifier.urihttps://doi.org/10.4317/medoral.23231
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10655
dc.identifier.volume25en_US
dc.identifier.wosWOS:000541535900014en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorUstaoğlu, Gülbahar
dc.institutionauthorAydın, Zeliha Uğur
dc.institutionauthorÖzelçi, Ferhat
dc.language.isoenen_US
dc.publisherMedicina Oral S Len_US
dc.relation.ispartofMedicina Oral Patologia Oral Y Cirugia Bucalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectFlap Surgeryen_US
dc.subjectGuided Tissue Regenerationen_US
dc.subjectIntrabony Defectsen_US
dc.subjectPeriodontitisen_US
dc.subjectRoot Canal Therapyen_US
dc.titleComparison of GTR, T-PRF and open-flap debridement in the treatment of intrabony defects with endo-perio lesions: a randomized controlled trialen_US
dc.typeArticleen_US

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