Comparison of GTR, T-PRF and open-flap debridement in the treatment of intrabony defects with endo-perio lesions: a randomized controlled trial
Yükleniyor...
Tarih
2020
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Medicina Oral S L
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: Titanium-prepared platelet rich fibrin (T-PRF) is an autologous hemo-component with a high concentration of platelets that also incorporates leukocytes, and growth factors into the dense fibrin matrix and can be used as a healing biomaterial. This study assesses the adjunctive use of T-PRF in intrabony defects ( IBDs) with open flap debridement (OFD) in comparison with guided tissue regeneration (GTR) as a gold standard and OFD alone as a control. Material and Methods: A total of 45 patients (15 per group) were randomized as either T-PRF (test group), GTR (test group), or OFD alone (control group) sites. Probing depth (PD), clinical attachment level (CAL), and IBD were recorded. The radiographic depth of IBD was also measured. Primary outcomes assessed were changes in PD, CAL, and radiographic IBD that were assessed at the beginning and nine months later. Results: The PRF and GTR group showed significant improvement in clinical parameters compared with the OFD alone (control group) at nine months. While there were no significant differences in PD and CAL between test groups (T-PRF and GTR groups), the significant difference was found in radiographic IBD depth. Conclusion: T-PRF may give similar successful results as GTR in the treatment of IBDs with endo-perio lesions.
Açıklama
Anahtar Kelimeler
Flap Surgery, Guided Tissue Regeneration, Intrabony Defects, Periodontitis, Root Canal Therapy
Kaynak
Medicina Oral Patologia Oral Y Cirugia Bucal
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
25
Sayı
1
