Effect of Royal Jelly on new bone formation in rapid maxillary expansion in rats

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dc.authorid0000-0002-0073-3170
dc.authorid0000-0002-3701-3484
dc.authorid0000-0002-5099-5128
dc.contributor.authorÖzan, Fatih
dc.contributor.authorÇörekçi, Bayram
dc.contributor.authorToptaş, Orçun
dc.contributor.authorHalıcıoğlu, Koray
dc.contributor.authorIrgın, Celal
dc.contributor.authorYılmaz, Fahri
dc.contributor.authorHezenci, Yasin
dc.date.accessioned2021-06-23T19:37:25Z
dc.date.available2021-06-23T19:37:25Z
dc.date.issued2015
dc.departmentBAİBÜ, Diş Hekimliği Fakültesi, Ağız Diş ve Çene Cerrahisi Ana Bilim Dalıen_US
dc.description.abstractBackground: The aim of this study was to evaluate the effects of long and short term systemic usage of royal jelly on bone formation in the expanded maxillary suture in a rat model. Material and Methods: Twenty eight Wistar albino rats were randomly divided into 4 equal groups: Control (C); Only Expansion (OE), Royal Jelly (RJ) group, Royal Jelly was given to rats by oral gavage only during the expansion and retention period; Royal Jelly plus Nursery (RJN) group, Royal Jelly was given to rats by oral gavage during their nursery phase of 40 days and during the retention period. After the 5 day expansion period was completed, the rats underwent 12 days of mechanical retention. All rats were sacrificed in same time. Histological examination was performed to determine the number of osteoclasts, number of osteoblasts, number of capillaries, inflammatory cell infiltration, and new bone formation. Results: New bone formation, number of osteoclasts, number of osteoblasts, and the number of capillaries in the expanded maxillary sutures were higher in the RJ and RJN groups than in the other groups. Statistical analysis also demonstrated that new bone formation and the number of osteoblasts was also highest in the RJN group. Conclusions: The systemic administration of Royal Jelly in conjunction with rapid maxillary expansion may increase the quality of regenerated bone.en_US
dc.identifier.doi10.4317/medoral.20581
dc.identifier.endpageE656en_US
dc.identifier.issn1698-6946
dc.identifier.issue6en_US
dc.identifier.pmid26449428en_US
dc.identifier.scopus2-s2.0-84945250350en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpageE651en_US
dc.identifier.urihttps://doi.org/10.4317/medoral.20581
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8158
dc.identifier.volume20en_US
dc.identifier.wosWOS:000369435500002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÖzan, Fatih
dc.institutionauthorÇörekçi, Bayram
dc.institutionauthorToptaş, Orçun
dc.institutionauthorHalıcıoğlu, Korauy
dc.institutionauthorIrgın, Celal
dc.institutionauthorYılmaz, Fahri
dc.institutionauthorHezenci, Yasin
dc.language.isoenen_US
dc.publisherMedicina Oral S Len_US
dc.relation.ispartofMedicina Oral Patologia Oral Y Cirugia Bucalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBone Formationen_US
dc.subjectRapid Maxillary Expansionen_US
dc.subjectRoyal Jellyen_US
dc.titleEffect of Royal Jelly on new bone formation in rapid maxillary expansion in ratsen_US
dc.typeArticleen_US

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