The role of the uncertainty of measurement of serum creatinine concentrations in the diagnosis of acute kidney injury

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dc.authorid0000-0001-7306-5233en_US
dc.authorid0000-0002-5924-7476
dc.authorid0000-0002-4542-4064
dc.authorid0000-0002-4313-8478
dc.contributor.authorTekçe, Buket Kin
dc.contributor.authorTekçe, Hikmet
dc.contributor.authorAktaş, Gülali
dc.contributor.authorÜyetürk, Uğur
dc.date.accessioned2021-06-23T19:44:30Z
dc.date.available2021-06-23T19:44:30Z
dc.date.issued2016
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractUncertainty of measurement is the numeric expression of the errors associated with all measurements taken in clinical laboratories. Serum creatinine concentration is the most common diagnostic marker for acute kidney injury. The goal of this study was to determine the effect of the uncertainty of measurement of serum creatinine concentrations on the diagnosis of acute kidney injury. We calculated the uncertainty of measurement of serum creatinine according to the Nordtest Guide. Retrospectively, we identified 289 patients who were evaluated for acute kidney injury. Of the total patient pool, 233 were diagnosed with acute kidney injury using the AKIN classification scheme and then were compared using statistical analysis. We determined nine probabilities of the uncertainty of measurement of serum creatinine concentrations. There was a statistically significant difference in the number of patients diagnosed with acute kidney injury when uncertainty of measurement was taken into consideration (first probability compared to the fifth p = 0.023 and first probability compared to the ninth p = 0.012). We found that the uncertainty of measurement for serum creatinine concentrations was an important factor for correctly diagnosing acute kidney injury. In addition, based on the AKIN classification scheme, minimizing the total allowable error levels for serum creatinine concentrations is necessary for the accurate diagnosis of acute kidney injury by clinicians.en_US
dc.identifier.doi10.3109/0886022X.2015.1117925
dc.identifier.endpage310en_US
dc.identifier.issn0886-022X
dc.identifier.issn1525-6049
dc.identifier.issue2en_US
dc.identifier.pmid26628060en_US
dc.identifier.scopus2-s2.0-84956887582en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage305en_US
dc.identifier.urihttps://doi.org/10.3109/0886022X.2015.1117925
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8996
dc.identifier.volume38en_US
dc.identifier.wosWOS:000378052200021en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorTekçe, Buket Kin
dc.institutionauthorTekçe, Hikmet
dc.institutionauthorAktaş, Gülali
dc.institutionauthorÜyetürk, Uğur
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofRenal Failureen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcute Kidney Injuryen_US
dc.subjectSerum Creatinineen_US
dc.subjectUncertainty of Measurementen_US
dc.subjectMarkeren_US
dc.subjectTotal Allowable Erroren_US
dc.titleThe role of the uncertainty of measurement of serum creatinine concentrations in the diagnosis of acute kidney injuryen_US
dc.typeArticleen_US

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