Systemic immune-inflammation index as a novel predictor of atrial fibrillation after off-pump coronary artery bypass grafting

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dc.authorid0000-0002-6107-2943en_US
dc.authorid0000-0003-4709-4705en_US
dc.authorid0000-0002-3779-2297en_US
dc.authorid0000-0002-6913-9073en_US
dc.authorid0000-0003-3655-1595en_US
dc.authorid0000-0003-4791-8946en_US
dc.contributor.authorTopal, Dursun
dc.contributor.authorKorkmaz, Ufuk Turan Kürşat
dc.contributor.authorVelioglu, Yusuf
dc.contributor.authorDönmez, İbrahim
dc.contributor.authorUçaroğlu, Erhan Renan
dc.contributor.authorKayış, Seyit Ali
dc.contributor.authorYüksel, Ahmet
dc.date.accessioned2023-07-28T08:20:06Z
dc.date.available2023-07-28T08:20:06Z
dc.date.issued2022en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractOBJECTIVE: This study aims to examine the predictive role of systemic immune-inflammation index on postoperative new-onset atrial fibrillation in patients undergoing off-pump coronary artery bypass grafting. METHODS: A total of 722 patients undergoing elective off-pump coronary artery bypass grafting between January 2017 and September 2021 were included in this study and divided into two groups as the atrial fibrillation group (n=172) and the non-atrial fibrillation group (n=550). Both groups were compared in terms of patients' baseline clinical features, operative and postoperative variables, and preoperative hematological indices derived from the complete blood count analysis. Multivariate logistic regression and receiver-operating characteristic curve analyses were performed to detect the independent predictors of postoperative new-onset atrial fibrillation. RESULTS: The median age and length of hospital stay in the atrial fibrillation group were significantly higher than those in the non-atrial fibrillation group. The median values of white blood cell, platelet, neutrophil, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and systemic immune -inflammation in the atrial fibrillation group were significantly greater than in those in the non-atrial fibrillation group. Logistic regression analysis demonstrated that age, platelet, platelet/lymphocyte ratio, and systemic immune-inflammation were independent predictors of postoperative new -onset atrial fibrillation. receiver-operating characteristic curve analysis revealed that systemic immune-inflammation of 706.7x103/mm3 constituted cut-off value to predict the occurrence of new-onset atrial fibrillation with 86.6% sensitivity and 29.3% specificity. CONCLUSION: Our study revealed for the first time that systemic immune-inflammation predicted new-onset atrial fibrillation after off-pump coronary artery bypass grafting.en_US
dc.identifier.citationTopal, D., Korkmaz, U. T. K., Velioglu, Y., Yuksel, A., Donmez, I., Uçaroğlu, E. R., & Kayis, S. A. (2022). Systemic immune-inflammation index as a novel predictor of atrial fibrillation after off-pump coronary artery bypass grafting. Revista da Associação Médica Brasileira, 68, 1240-1246.en_US
dc.identifier.doi10.1590/1806-9282.20220295
dc.identifier.endpage1246en_US
dc.identifier.issn0104-4230
dc.identifier.issn1806-9282
dc.identifier.issue9en_US
dc.identifier.pmid36228255en_US
dc.identifier.scopus2-s2.0-85139787607en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1240en_US
dc.identifier.urihttp://dx.doi.org/10.1590/1806-9282.20220295
dc.identifier.urihttps://hdl.handle.net/20.500.12491/11389
dc.identifier.volume68en_US
dc.identifier.wosWOS:000877660200019en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKorkmaz, Ufuk Turan Kürşat
dc.institutionauthorDönmez, İbrahim
dc.institutionauthorVelioglu, Yusuf
dc.institutionauthorKayış, Seyit Ali
dc.language.isoenen_US
dc.publisherAssoc Medica Brasileiraen_US
dc.relation.ispartofRevista da Associacao Medica Brasileiraen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAtrial Fibrillationen_US
dc.subjectOff Pump Coronary Artery Bypassen_US
dc.subjectNew-Onset; Lymphocyte Ratioen_US
dc.subjectPrognostic Valueen_US
dc.subjectSurgeryen_US
dc.subjectMortalityen_US
dc.titleSystemic immune-inflammation index as a novel predictor of atrial fibrillation after off-pump coronary artery bypass graftingen_US
dc.typeArticleen_US

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