Effects of tibolone on blood flow resistance and intima-media thickness of the carotid arteries: effect of time since menopause

Basit Öğe Kaydı
dc.authorid0000-0002-5511-2654
dc.contributor.authorSomunkıran, Aslı
dc.contributor.authorYazıcı, Burhan
dc.contributor.authorDemirci, Fuat
dc.contributor.authorErdoğmuş, Beşir
dc.contributor.authorÖzdemir, İsmail
dc.date.accessioned2021-06-23T19:19:21Z
dc.date.available2021-06-23T19:19:21Z
dc.date.issued2006
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description21st Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology -- JUN 19-22, 2005 -- Copenhagen, DENMARKen_US
dc.description.abstractObjective The aim of this prospective study was to evaluate the effects of tibolone on carotid atherosclerosis in healthy postmenopausal women. Methods Twenty-five healthy postmenopausal women were included in the study. Patients received tibolone 2.5 mg daily for 6 months. Resistance indices of the common carotid artery (CCA), internal carotid artery (ICA), external carotid artery (ECA) and vertebral arteries, and intima-media thickness of the CCA were measured both at baseline and at the end of the study with ultrasonography. Results No significant differences were observed in the resistance indices of the CCA, ICA, ECA and vertebral arteries, as well as intima-media thickness of CCA at 6 months in comparison with baseline. Tibolone significantly improved the intima-media thickness of the CCA of women who were less than 18 months since menopause. Conclusion Overall, these results demonstrate no significant effects of tibolone on either intima-media thickness or blood flow resistance in the carotid arteries in postmenopausal women. However, the results suggest that tibolone may have a positive effect on the vascular system if commenced within 18 months since menopause; this warrants further investigation.en_US
dc.description.sponsorshipEuropean Soc Human Reprod & Embryolen_US
dc.identifier.doi10.1080/13697130500505223
dc.identifier.endpage65en_US
dc.identifier.issn1369-7137
dc.identifier.issn1473-0804
dc.identifier.issue1en_US
dc.identifier.pmid16428126en_US
dc.identifier.scopus2-s2.0-31544450032en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage59en_US
dc.identifier.urihttps://doi.org/10.1080/13697130500505223
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5926
dc.identifier.volume9en_US
dc.identifier.wosWOS:000235323300008en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorSomunkıran, Aslı
dc.institutionauthorYazıcı, Burhan
dc.institutionauthorDemirci, Fuat
dc.institutionauthorErdoğmuş, Beşir
dc.institutionauthorÖzdemir, İsmail
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofClimactericen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCarotid Arteriesen_US
dc.subjectIntima-media Thicknessen_US
dc.subjectMenopauseen_US
dc.subjectTiboloneen_US
dc.titleEffects of tibolone on blood flow resistance and intima-media thickness of the carotid arteries: effect of time since menopauseen_US
dc.typeConference Objecten_US

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