Could red cell distribution width be a marker in Hashimoto's Thyroiditis?

dc.authorid0000-0001-7306-5233en_US
dc.authorid0000-0002-3156-1076en_US
dc.authorid0000-0002-5924-7476
dc.contributor.authorAktaş, Gülali
dc.contributor.authorŞit, Mustafa
dc.contributor.authorDikbaş, Oğuz
dc.contributor.authorTekçe, Buket Kin
dc.contributor.authorSavlı, Haluk
dc.contributor.authorTekçe, Hikmet
dc.contributor.authorAlçelik, Aytekin
dc.date.accessioned2021-06-23T19:35:21Z
dc.date.available2021-06-23T19:35:21Z
dc.date.issued2014
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractAims: Hashimoto's Thyroiditis (HT) is the most common autoimmune thyroiditis worldwide and characterized with lymphomonocytic inflammation of the thyroid gland. Red cell distribution width (RDW) reflects erythrocyte anisocytosis and besides it increases in iron deficiency anemia, recent studies reported that RDW was also associated with conditions characterized with overt or subclinical infl ammation. We aimed to answer whether RDW increased in Hashimoto's thyroiditis. Methods: Patients with HT admitted to outpatient clinic of our hospital were included to the study. Patients with anemia (especially iron deficiency), diabetes mellitus, chronic inflammatory disease and on medication that may affect hemogram results (e.g., aspirin) excluded from the study. Patient characteristics, thyroid stimulating hormone (TSH), Free T3 (FT3), Free T4 (FT4), Anti-thyroid peroxidase (Anti-TPO), Anti-Thyroglobulin (Anti-TG), leukocyte count (WBC), Hemoglobin (Hb), Hematocrit (Htc), mean corpuscular volume (MCV), RDW and platelet count (PLT) values of the study cohort were obtained from computerized database of our institution. Results: There was no significant difference between study and control groups in terms of WBC, Hb, Htc, MCV, PLT, PDW and FT3 levels. However, FT4 level was significantly lower and TSH was significantly higher in study group compared to controls. RDW was significantly increased in study group compared to control group. Conclusion: We suggest that elevated RDW values in patients without iron deficiency anemia may require further evaluation for HT, especially in female population.en_US
dc.identifier.doi10.1055/s-0034-1383564
dc.identifier.endpage574en_US
dc.identifier.issn0947-7349
dc.identifier.issn1439-3646
dc.identifier.issue10en_US
dc.identifier.pmid25380549en_US
dc.identifier.scopus2-s2.0-84909606881en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage572en_US
dc.identifier.urihttps://doi.org/10.1055/s-0034-1383564
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7769
dc.identifier.volume122en_US
dc.identifier.wosWOS:000346273400004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAktaş, Gülali
dc.institutionauthorŞit, Mustafa
dc.institutionauthorDikbaş, Oğuz
dc.institutionauthorTekçe, Buket Kin
dc.institutionauthorSavlı, Haluk
dc.institutionauthorTekçe, Hikmet
dc.institutionauthorAlçelik, Aytekin
dc.language.isoenen_US
dc.publisherJohann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbhen_US
dc.relation.ispartofExperimental And Clinical Endocrinology & Diabetesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHashimoto's Thyroiditisen_US
dc.subjectRed Cell Distribution Widthen_US
dc.subjectInflammationen_US
dc.titleCould red cell distribution width be a marker in Hashimoto's Thyroiditis?en_US
dc.typeArticleen_US

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