Does mean platelet volume/lymphocyte count ratio associate with frailty in type 2 diabetes mellitus?
Yükleniyor...
Dosyalar
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Comenius University in Bratislava
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
OBJECTIVES: Frailty is a common problem in patients with type 2 diabetes mellitus (T2DM). It is considered to be associated with inflammation. Novel markers derived from hemogram, such as neutrophil/lymphocyte ratio (NLR) and mean platelet volume/lymphocyte ratio (MPVLR), are proposed as inflammatory markers. In present study, we aimed to compare NLR and MPVLR levels of frail patients with T2DM to non-frail diabetic subjects. METHODS: Diabetic subjects were grouped in frail and non-frail groups according to the Edmonton Frail Scale. General characteristics and laboratory data of the frail and non-frail groups were compared. RESULTS: The MPVLR of the frail (3.9 [1.4–13.2] %) group was significantly higher than that of the non-frail (3.4 [1.5–6.9] %) group (p = 0.02). MPVLR was positively and significantly correlated with Edmonton Frail Scale score (r = 0.21, p = 0.03). A MPVLR level greater than 3.41 % has 71 % sensitivity and 51 % specify in predicting frailty. CONCLUSION: We suggest that elevated MPVLR could be a finding that marks frailty in diabetic subjects. Inexpensive and easy-to-assess nature of the MPVLR may be useful in predicting frailty in type 2 diabetic population (Tab. 2, Fig. 1, Ref. 32). Text in PDF www.elis.sk
Açıklama
Anahtar Kelimeler
Frailty, Inflammation, Mean Platelet Volume/Lymphocyte Ratio, Type 2 Diabetes Mellitus
Kaynak
Bratislava Medical Journal
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
122
Sayı
2
