Cerebrospinal fluid signal loss sign: Assessment of a new radiological sign in lumbar spinal stenosis

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dc.authorid0000-0002-4888-0962en_US
dc.authorid0000-0002-7999-8058en_US
dc.authorid0000-0003-2183-7080en_US
dc.authorid0000-0002 -9750-9350en_US
dc.contributor.authorHızal, Mustafa
dc.contributor.authorÖzdemir, Faruk
dc.contributor.authorKalaycıoğlu, Oya
dc.contributor.authorIşık, Cengiz
dc.date.accessioned2023-06-05T08:54:55Z
dc.date.available2023-06-05T08:54:55Z
dc.date.issued2021en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractPurpose Sedimentation sign was reported to have high sensitivity and specificity for diagnosis of lumbar spinal stenosis (LSS). We aimed to determine cerebrospinal fluid signal loss (CSFSL) at the intervertebral disc levels in the sagittal plane using a numerical scoring system and to evaluate the diagnostic value of this method in differential diagnosis of LSS and non-specific low back pain (LBP) and compare it with SS. Materials and methods We included consecutive patients between 50 and 80 years old, with lumbar spinal MRI examination in our institution. These patients were divided into two groups as LSS and LBP, according to symptoms and radiological findings. CSFSL sign was evaluated for both groups by two radiologists independently, using MR images. Sensitivity and specificity of both signs were calculated. Results A total of 406 patients (98 LSS and 308 non-specific LBP) were included. SS and CSFSL sign had a sensitivity of 90.8% and 82.7% and specificity of 75.4% and 84.1% in the whole cohort, respectively. When patients were grouped by dural sac cross-sectional areas (CSA), sensitivity and specificity of SS were 100% and 4.4%, 87.5% and 31.8%, and 41.7% and 76%, respectively, and sensitivity and specificity of CSFSL sign were 95.7% and 11.1%, 75% and 77.3%, and 16.7 and 92% for severe (CSA < 80 mm2), moderate (CSA: 80-100 mm2), mild (CSA: 100-120 mm2) radiologic stenosis, respectively. In moderate stenosis, accuracies of SS and CSFSL sign were 76.3% and 55.3%, respectively. Conclusion CSFSL sign might be used to distinguish LSS from LBP and unlike SS it is successful in moderate stenosis.en_US
dc.identifier.citationHızal, M., Özdemir, F., Kalaycıoğlu, O., & Işık, C. (2021). Cerebrospinal fluid signal loss sign: assessment of a new radiological sign in lumbar spinal stenosis. European Spine Journal, 30, 3297-3306.en_US
dc.identifier.doi10.1007/s00586-021-06929-7
dc.identifier.endpage3306en_US
dc.identifier.issn0940-6719
dc.identifier.issn1432-0932
dc.identifier.issue11en_US
dc.identifier.pmid34283305en_US
dc.identifier.scopus2-s2.0-85110803094en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage3297en_US
dc.identifier.urihttp://dx.doi.org/10.1007/s00586-021-06929-7
dc.identifier.uriWOS:000675138300001
dc.identifier.urihttps://hdl.handle.net/20.500.12491/11059
dc.identifier.volume30en_US
dc.identifier.wosWOS:000675138300001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorHızal, Mustafa
dc.institutionauthorÖzdemir, Faruk
dc.institutionauthorKalaycıoğlu, Oya
dc.institutionauthorIşık, Cengiz
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Spine Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLumbar Spinal Stenosisen_US
dc.subjectMagnetic Resonance Imagingen_US
dc.subjectDiagnostic Testen_US
dc.subjectSedimentation Testen_US
dc.subjectCerebrospinal Fluid Signalen_US
dc.titleCerebrospinal fluid signal loss sign: Assessment of a new radiological sign in lumbar spinal stenosisen_US
dc.typeArticleen_US

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