Serum levels of omentin in pseudoexfoliation syndrome

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dc.authorid0000-0003-1657-9099en_US
dc.contributor.authorBucak, Yasin Yücel
dc.contributor.authorTosun, Mehmet
dc.contributor.authorSimavli, Hüseyin
dc.contributor.authorÖnder, Halil İbrahim
dc.contributor.authorErdurmuş, Mesut
dc.date.accessioned2021-06-23T19:43:53Z
dc.date.available2021-06-23T19:43:53Z
dc.date.issued2016
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractPurpose: Omentin, a member of the adipocytokines family, is derived from adipose tissue and a lower level of serum omentin is considered as a metabolic risk factor. The aim of the present study is to evaluate the serum levels of omentin in patients with pseudoexfoliation syndrome (PES). Materials and Methods: Patients without any systemic or ocular disease other than PES were included in the study. Age-matched and sex-matched healthy volunteers without PES were accepted as a control group. After detailed ophthalmologic examination, blood samples were obtained from a forearm vein. Serum levels of omentin were determined by the method of enzyme-linked immunosorbent assay. Results: The mean age of the PES group (12 females, 12 males, n = 24) was 75.2 +/- 8.4 years, and the control group (10 females, 10 males, n = 20) was 75 +/- 6.7 years. There was no difference between the groups in terms of age (P = 0.93) and sex (P = 0.9). The mean serum levels of omentin in the PES group were 801.5 +/- 317.1 ng/mL and in the control group were 1150.1 +/- 584.1 ng/mL. The mean serum omentin levels were significantly lower in patients with PES (P = 0.016). Conclusion: Lower levels of serum omentin in patients with PES compared with healthy subjects may support the theory of systemic nature of the disease.en_US
dc.identifier.doi10.1097/IJG.0000000000000139
dc.identifier.endpage148en_US
dc.identifier.issn1057-0829
dc.identifier.issn1536-481X
dc.identifier.issue2en_US
dc.identifier.pmid25264991en_US
dc.identifier.scopus2-s2.0-84957437359en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage145en_US
dc.identifier.urihttps://doi.org/10.1097/IJG.0000000000000139
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8872
dc.identifier.volume25en_US
dc.identifier.wosWOS:000374819800014en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorErdurmuş, Mesut
dc.institutionauthorTosun, Mehmet
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofJournal Of Glaucomaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPseudoexfoliation Syndromeen_US
dc.subjectOmentinen_US
dc.subjectBody Mass Indexen_US
dc.titleSerum levels of omentin in pseudoexfoliation syndromeen_US
dc.typeArticleen_US

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