Histopathological evaluation of the effect of intranasal phototherapy on nasal mucosa in rabbits

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dc.contributor.authorApuhan, Tayfun
dc.contributor.authorTerzi, Elçin Hakan
dc.contributor.authorKükner, Aysel
dc.contributor.authorGök, Üzeyir
dc.date.accessioned2021-06-23T19:27:38Z
dc.date.available2021-06-23T19:27:38Z
dc.date.issued2011
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractAllergic rhinitis is a high-incidence allergic inflammation of the nasal airways that impacts quality of life. Of the numerous therapies used to treat allergic rhinitis, intranasal phototherapy has emerged as a promising new treatment modality for inflammatory airway disease. Phototherapy is widely used for the treatment of immune-mediated skin diseases because its profound immunosuppressive effect inhibits hypersensitivity reactions in the skin. Intranasal phototherapy using a combination of Ultraviolet-A (UVA) and Ultraviolet-B (UVB) plus Visible light (VIS) has been shown to suppress the clinical symptoms of allergic rhinitis, but limited data regarding its adverse effects on the nasal mucosa currently exists. In this study, we demonstrate that UV displays no harmful effects on the nasal mucosa cells of rabbits following 2 weeks of intranasal phototherapy. (C) 2011 Elsevier B.V. All rights reserved.en_US
dc.identifier.doi10.1016/j.jphotobiol.2011.07.006
dc.identifier.endpage97en_US
dc.identifier.issn1011-1344
dc.identifier.issue1en_US
dc.identifier.pmid21890373en_US
dc.identifier.scopus2-s2.0-80052963814en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage94en_US
dc.identifier.urihttps://doi.org/10.1016/j.jphotobiol.2011.07.006
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6860
dc.identifier.volume105en_US
dc.identifier.wosWOS:000295706000014en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorApuhan, Tayfun
dc.institutionauthorTerzi, Elçin Hakan
dc.institutionauthorKükner, Aysel
dc.institutionauthorGök, Üzeyir
dc.language.isoenen_US
dc.publisherElsevier Science Saen_US
dc.relation.ispartofJournal Of Photochemistry And Photobiology B-Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRhinophototherapyen_US
dc.subjectRabbitsen_US
dc.subjectAllergic rhinitisen_US
dc.subjectUltraviolet radiationen_US
dc.titleHistopathological evaluation of the effect of intranasal phototherapy on nasal mucosa in rabbitsen_US
dc.typeArticleen_US

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