Histopathological evaluation of the effect of intranasal phototherapy on nasal mucosa in rabbits

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Küçük Resim

Tarih

2011

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Elsevier Science Sa

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Allergic rhinitis is a high-incidence allergic inflammation of the nasal airways that impacts quality of life. Of the numerous therapies used to treat allergic rhinitis, intranasal phototherapy has emerged as a promising new treatment modality for inflammatory airway disease. Phototherapy is widely used for the treatment of immune-mediated skin diseases because its profound immunosuppressive effect inhibits hypersensitivity reactions in the skin. Intranasal phototherapy using a combination of Ultraviolet-A (UVA) and Ultraviolet-B (UVB) plus Visible light (VIS) has been shown to suppress the clinical symptoms of allergic rhinitis, but limited data regarding its adverse effects on the nasal mucosa currently exists. In this study, we demonstrate that UV displays no harmful effects on the nasal mucosa cells of rabbits following 2 weeks of intranasal phototherapy. (C) 2011 Elsevier B.V. All rights reserved.

Açıklama

Anahtar Kelimeler

Rhinophototherapy, Rabbits, Allergic rhinitis, Ultraviolet radiation

Kaynak

Journal Of Photochemistry And Photobiology B-Biology

WoS Q Değeri

Q2

Scopus Q Değeri

Q1

Cilt

105

Sayı

1

Künye