The diagnostic significance of NT-proBNP and troponin I in emergency department patients presenting with palpitations

Basit Öğe Kaydı
dc.authorid0000-0002-2119-9448en_US
dc.contributor.authorOcak, Tarık
dc.contributor.authorErdem, Alim
dc.contributor.authorDuran, Arif
dc.contributor.authorTekelioğlu, Ümit Yaşar
dc.contributor.authorÖztürk, Serkan
dc.contributor.authorAyhan, Suzi Selim
dc.contributor.authorÖzlü, Mehmet Fatih
dc.contributor.authorTosun, Mehmet
dc.contributor.authorKoçoğlu, Hasan
dc.contributor.authorYazıcı, Mehmet
dc.date.accessioned2021-06-23T19:35:05Z
dc.date.available2021-06-23T19:35:05Z
dc.date.issued2013
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractOBJECTIVE: This prospective study investigated the diagnostic significance of the N-terminal pro-brain natriuretic (NT-proBNP) and troponin I peptides in emergency department patients presenting with palpitations. METHODS: Two groups of patients with palpitations but without documented supraventricular tachycardia were compared: a group with supraventricular tachycardia (n = 49) and a control group (n = 47). Both groups were diagnosed using electrophysiological studies during the study period. Blood samples were obtained from all of the patients to determine the NT-proBNP and troponin I levels within the first hour following arrival in the emergency department. RESULT: The mean NT-proBNP levels were 207.74 +/- 197.11 in supraventricular tachyarrhythmia group and 39.99 +/- 32.83 pg/mL in control group (p<0.001). To predict supraventricular tachycardia, the optimum NT-proBNP threshold was 61.15 pg/mL, as defined by the receiver operating characteristic (ROC) curve, with a non-significant area under the ROC curve of 0.920 (95% CI, 0.86-0.97, p<0.001). The NT-proBNP cut-off for diagnosing supraventricular tachycardia had 81.6% sensitivity and 91.5% specificity. Supraventricular tachycardia was significantly more frequent in the patients with NT-proBNP levels >= 61.15 pg/mL (n = 44, 90.9%, p>0.001). The mean troponin I levels were 0.17 +/- 0.56 and 0.01 +/- 0.06 pg/mL for the patients with and without supraventricular tachycardia, respectively (p<0.05). Of the 96 patients, 21 (21.87%) had troponin I levels >= 0.01:2 (4.25%) in the control group and 19 (38.77%) in the supraventricular tachycardia group (p<0.001). CONCLUSION: Troponin I and, in particular, NT-proBNP peptide were helpful for differentiating supraventricular tachycardia from non-supraventricular tachycardia palpitations. Further randomized, large, multicenter trials are needed to define the benefit and diagnostic role of NT-proBNP and troponin I in the management algorithm of patients presenting with palpitations in emergency departments.en_US
dc.identifier.endpage547en_US
dc.identifier.issn1807-5932
dc.identifier.issue4en_US
dc.identifier.pmid23778331en_US
dc.identifier.scopus2-s2.0-84878116922en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage543en_US
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634957/
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7707
dc.identifier.volume68en_US
dc.identifier.wosWOS:000320002000017en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorOcak, Tarık
dc.institutionauthorErdem, Alim
dc.institutionauthorDuran, Arif
dc.institutionauthorTekelioğlu, Ümit Yaşar
dc.institutionauthorÖztürk, Serkan
dc.institutionauthorAyhan, Suzi Selim
dc.institutionauthorÖzlü, Mehmet Fatih
dc.institutionauthorTosun, Mehmet
dc.institutionauthorKoçoğlu, Hasan
dc.institutionauthorYazıcı, Mehmet
dc.language.isoenen_US
dc.publisherHospital Clinicas, Univ Sao Pauloen_US
dc.relation.ispartofClinicsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectN-terminal of Brain Natriuretic Peptideen_US
dc.subjectTroponin Ien_US
dc.subjectPalpitationsen_US
dc.subjectSupraventricular Tachycardiaen_US
dc.titleThe diagnostic significance of NT-proBNP and troponin I in emergency department patients presenting with palpitationsen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
tarik-ocak-7707.pdf
Boyut:
736.63 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam metin/Full text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Cerrahi Tıp Bilimleri Bölümü Koleksiyonu
Dahili Tıp Bilimleri Bölümü Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Temel Tıp Bilimleri Bölümü Koleksiyonu