Serum amyloid a and omentin levels in acute appendicitis: a preliminary study for a novel diagnostic approach

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dc.authorid0000-0002-7475-7298
dc.authorid0000-0001-7306-5233
dc.authorid0000-0003-4318-9619
dc.authorid0000-0002-7422-1442
dc.contributor.authorŞit, Mustafa
dc.contributor.authorÇatal, Oğuz
dc.contributor.authorAktaş, Gülali
dc.contributor.authorYılmaz, Edip Erdal
dc.contributor.authorTosun, Mehmet
dc.contributor.authorŞavlı, Haluk
dc.date.accessioned2021-06-23T18:55:30Z
dc.date.available2021-06-23T18:55:30Z
dc.date.issued2014
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractBacground: The diagnosis of acute appendicitis is based on medical history and physical examination. Serum (S) amiloid A (AA) levels are elevated in many inflammatory conditions. Omentin is a recently discovered adipokine showing decreased levels associated with inflammatory conditions. We aimed to measure SAA and omentin levels in patients with acute appendicitis. Materials and Methods: 36 patients with a diagnosis of acute appendicitis and 30 healthy subjects were enrolled to this research study. A statistical analysis was performed using IBM SPSS Statistics Version 16.0 (SPSS Inc.®, Chicago, IL, United States). Results: Patients in study group were significantly older than healthy control subjects (p=0.013). Body mass index of the patients with acute appendicitis (23.2±1.3) was greater than that of the control group (22.7±1), but the difference did not reach the statistically significance (p=0.076). ). Mean level of SAA was significantly raised in study group compared to healthy control subjects (p<0.001). Mean omentin level was significantly lower in study group compared to healthy subjects (p=0.013). Conclusions: In conclusion, although diagnosis of acute appendicitis is mostly based on clinical findings, omentin and especially SAA measurement in serum may help surgeons to avoid negative laparatomy.en_US
dc.identifier.doi10.7471/CT.2014.1669
dc.identifier.endpagee38en_US
dc.identifier.issn0009-9074
dc.identifier.issue1 SUPPLen_US
dc.identifier.pmid24589958en_US
dc.identifier.scopus2-s2.0-84896304346en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpagee35en_US
dc.identifier.urihttps://doi.org/10.7471/CT.2014.1669
dc.identifier.urihttps://hdl.handle.net/20.500.12491/4789
dc.identifier.volume165en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorŞit, Mustafa
dc.institutionauthorAktaş, Gülali
dc.institutionauthorYılmaz, Edip Erdal
dc.institutionauthorTosun, Mehmet
dc.institutionauthorŞavlı, Haluk
dc.language.isoenen_US
dc.publisherSocieta Editrice Universoen_US
dc.relation.ispartofClinica Terapeuticaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute Appendicitisen_US
dc.subjectOmentinen_US
dc.subjectSerum Amyloid Aen_US
dc.titleSerum amyloid a and omentin levels in acute appendicitis: a preliminary study for a novel diagnostic approachen_US
dc.typeArticleen_US

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