Serum amyloid a and omentin levels in acute appendicitis: a preliminary study for a novel diagnostic approach
Yükleniyor...
Dosyalar
Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Societa Editrice Universo
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Bacground: The diagnosis of acute appendicitis is based on medical history and physical examination. Serum (S) amiloid A (AA) levels are elevated in many inflammatory conditions. Omentin is a recently discovered adipokine showing decreased levels associated with inflammatory conditions. We aimed to measure SAA and omentin levels in patients with acute appendicitis. Materials and Methods: 36 patients with a diagnosis of acute appendicitis and 30 healthy subjects were enrolled to this research study. A statistical analysis was performed using IBM SPSS Statistics Version 16.0 (SPSS Inc.®, Chicago, IL, United States). Results: Patients in study group were significantly older than healthy control subjects (p=0.013). Body mass index of the patients with acute appendicitis (23.2±1.3) was greater than that of the control group (22.7±1), but the difference did not reach the statistically significance (p=0.076). ). Mean level of SAA was significantly raised in study group compared to healthy control subjects (p<0.001). Mean omentin level was significantly lower in study group compared to healthy subjects (p=0.013). Conclusions: In conclusion, although diagnosis of acute appendicitis is mostly based on clinical findings, omentin and especially SAA measurement in serum may help surgeons to avoid negative laparatomy.
Açıklama
Anahtar Kelimeler
Acute Appendicitis, Omentin, Serum Amyloid A
Kaynak
Clinica Terapeutica
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
165
Sayı
1 SUPPL
