Cord blood lipoprotein profile after magnesium sulphate treatment in pre-eclamptic patients

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dc.authorid0000-0003-0694-9180
dc.authorid0000-0003-1937-9244
dc.contributor.authorYavuz, Taner
dc.contributor.authorYavuz, Özlem
dc.contributor.authorÖzdemir, İsmail
dc.contributor.authorAfşar, Yılmaz
dc.date.accessioned2021-06-23T19:18:50Z
dc.date.available2021-06-23T19:18:50Z
dc.date.issued2006
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractAim: To determine lipoprotein metabolism alterations in magnesium-exposed neonates of women with pre-eclampsia. Methods: The study group comprised seven singleton neonates of women with pre-eclampsia at term and treated with magnesium sulphate. Controls were 26 neonates of uncomplicated pregnancies of term delivery. Total serum magnesium concentrations were analysed by the photometric colour method. Total serum cholesterol, triglycerides and high-density lipoprotein cholesterol ( HDL-C) levels were determined by enzymatic colour methods, while apoprotein ( apo)A-I and apo B values were measured by immunoturbidimetry. Low-density lipoprotein cholesterol ( LDL-C) levels were calculated by Friedewald's formula. Very-low-density lipoprotein cholesterol levels, total cholesterol/HDL-C, apo B/apo A-I, LDL-C/apo B, LDL-C/HDL-C, and HDL-C/apo A-I ratios were determined by calculation. Results: Magnesium levels of magnesium-exposed neonates were found to be 1.6 times higher than those of controls. Magnesium-exposed neonates had lower serum apo A-I levels, and they had higher apo B/apo A-I and HDL-C/apo A-I ratios when compared to controls. Conclusion: The lipoprotein profile became more atherogenic in magnesium-exposed neonates as it may be a potential risk factor of cardiovascular heart disease.en_US
dc.identifier.doi10.1080/08035250600589017
dc.identifier.endpage1227en_US
dc.identifier.issn0803-5253
dc.identifier.issn1651-2227
dc.identifier.issue10en_US
dc.identifier.pmid16982494en_US
dc.identifier.scopus2-s2.0-33748859886en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1224en_US
dc.identifier.urihttps://doi.org/10.1080/08035250600589017
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5819
dc.identifier.volume95en_US
dc.identifier.wosWOS:000240562000013en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYavuz, Taner
dc.institutionauthorYavuz, Özlem
dc.institutionauthorÖzdemir, İsmail
dc.institutionauthorAfşar, Yılmaz
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofActa Paediatricaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectApoproteinen_US
dc.subjectCord Blooden_US
dc.subjectLipoproteinen_US
dc.subjectMagnesium Sulphateen_US
dc.subjectNeonateen_US
dc.titleCord blood lipoprotein profile after magnesium sulphate treatment in pre-eclamptic patientsen_US
dc.typeArticleen_US

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