The relationship between epicardial fat thickness and high-grade varicocele

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dc.authorid0000-0003-2399-9585
dc.authorid0000-0002-3893-5376
dc.authorid0000-0001-7858-0672
dc.authorid0000-0002-0462-3171
dc.authorid0000-0003-3817-851X
dc.contributor.authorSincer, İsa
dc.contributor.authorErdal, Emrah
dc.contributor.authorGücük, Adnan
dc.contributor.authorBostancı, Emre
dc.contributor.authorGüneş, Yılmaz
dc.date.accessioned2021-06-23T18:57:24Z
dc.date.available2021-06-23T18:57:24Z
dc.date.issued2020
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractBackground: Varicocele is abnormal dilation of testis veins. The precise mechanism of varicocele is not fully understood despite some hypothesis were suggested in the literature. Disequilibrium between constrictor and dilatator mechanism of the veins have been shown to cause varicocele. High-grade varicoceles have been also linked to endothelial dysfunction and increased vasoconstriction. Objectives: We hypothesized that epicardial fat thickness (EFT), flow-mediated dilatation (FMD) and aortic stiffness (AS) could be associated with varicocele. In the present study, we aimed to compare vascular parameters such as FMD, EFT and AS in healthy subjects and high-grade varicocele patients. Methods: The study population consisted of 35 men with high-grade varicocele and 32 age-and sex-matched control subjects younger than 45 years old. This is a cross-sectional study conducted at Bolu Abant Izzet Baysal University Hospital between May to October 2018. Results: EFT, aortic diastolic diameters (AoDD) and EFT/BMI ratio were significantly higher in control group than in patients with high-grade (p=0.012, p=0.044, p=0.026, respectively). EFT and EFT /BMI ratio were significantly and inversely correlated with presence of varicocele (r=-0.422, p=0.009; r=-0.38, p=0.026, respectively). Conclusion: The present study suggests that high-grade varicocele may be associated with decreased echocardiographic EFT but not with aortic stiffness and FMD.en_US
dc.identifier.doi10.4314/ahs.v20i4.28
dc.identifier.endpage1760en_US
dc.identifier.issn1680-6905
dc.identifier.issue4en_US
dc.identifier.pmid34394236en_US
dc.identifier.scopus2-s2.0-85098088679en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1754en_US
dc.identifier.urihttps://doi.org/10.4314/ahs.v20i4.28
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5183
dc.identifier.volume20en_US
dc.identifier.wosWOS:000631822500026en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorSincer, İsa
dc.institutionauthorErdal, Emrah
dc.institutionauthorGücük, Adnan
dc.institutionauthorBostancı, Emre
dc.institutionauthorGüneş, Yılmaz
dc.language.isoenen_US
dc.publisherMakerere University, Medical Schoolen_US
dc.relation.ispartofAfrican Health Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAortic Stiffnessen_US
dc.subjectFlow-mediated Dilatationen_US
dc.subjectHigh-grade Varicoceleen_US
dc.subjectEpicardial Fat Thicknessen_US
dc.titleThe relationship between epicardial fat thickness and high-grade varicoceleen_US
dc.typeArticleen_US

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