Influence of different anti-hypertensive drugs on gingival overgrowth: cross-sectional study in a Turkish population

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dc.authorid0000-0002-3893-5376en_US
dc.authorid0000-0002-4205-861X
dc.contributor.authorUstaoğlu, Gülbahar
dc.contributor.authorErdal, Emrah
dc.contributor.authorKaraş, Zeynep
dc.date.accessioned2021-06-23T19:17:09Z
dc.date.available2021-06-23T19:17:09Z
dc.date.issued2020
dc.departmentBAİBÜ, Diş Hekimliği Fakültesi, Periodontoloji Ana Bilim Dalıen_US
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü
dc.description.abstractObjective The purpose of this study was to evaluate the occurrence rate of drug-induced gingival overgrowth (DIGO) in patients treated with angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), and calcium channel blockers (CCBs) such as amlodipine, lercanidipine, and benidipine, as well as to assess the relationship of those mentioned above with medication variables and oral hygiene. Methods Sociodemographic details, DIGO, and clinical periodontal parameters were obtained from one hundred and thirty-one patients receiving ACE inhibitors, ARBs, and CCBs for a period of at least 2 years. Results The occurrence rate of DIGO was 19.6% in patients using CCB, 12.5% in the ARB group, and 7.5% in the ACE inhibitor group. In a subgroup analysis of CCBs, DIGO was found to be 31.8% in the amlodipine group, 13.3% in the lercanidipine group, and 7.1% in the benidipine group. While there was a significant relationship between amlodipine drug dosage and DIGO, no association was found between the duration of therapy and DIGO in all CCB subgroups. Conclusion There was no difference between the groups in terms of DIGO. Duration of therapy and drug dosage did not affect the severity of DIGO in both ACE inhibitors and ARB groups.en_US
dc.identifier.doi10.1111/odi.13655
dc.identifier.endpage1319
dc.identifier.issn1354-523X
dc.identifier.issue5
dc.identifier.pmid32991012en_US
dc.identifier.scopus2-s2.0-85092928440en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1313
dc.identifier.urihttps://doi.org/10.1111/odi.13655
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5249
dc.identifier.volume27
dc.identifier.wosWOS:000579878300001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorUstaoğlu, Gülbahar
dc.institutionauthorErdal, Emrah
dc.institutionauthorKaraş, Zeynep
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofOral Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAngiotensin-converting Enzyme Inhibitorsen_US
dc.subjectCalcium Channel Blockersen_US
dc.subjectAngiotensin Receptor Blockersen_US
dc.subjectGingival Overgrowthen_US
dc.subjectHypertensionen_US
dc.titleInfluence of different anti-hypertensive drugs on gingival overgrowth: cross-sectional study in a Turkish populationen_US
dc.typeArticleen_US

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