Interpretation of biochemical tests using the reference change value in monitoring adverse effects of oral isotretinoin in 102 ethnic Turkish patients

Basit Öğe Kaydı
dc.authorid0000-0002-4060-3354en_US
dc.authorid0000-0001-9226-5134
dc.authorid0000-0002-7161-2907
dc.contributor.authorBuğdaycı, Güler
dc.contributor.authorPolat, Mualla
dc.contributor.authorOğuzman, Hamdi
dc.contributor.authorÇinpolat, Havva Yasemin
dc.date.accessioned2021-06-23T19:43:15Z
dc.date.available2021-06-23T19:43:15Z
dc.date.issued2016
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü
dc.description.abstractObjectives: The aim of this study was to model the use of reference change values (RCVs) for the follow-up of 4 parameters of patients using oral isotretinoin which is gaining widespread popularity for monitoring the side effects of the treatment. Method: 102 patients received 30 mg/day oral isotretinoin for 24 weeks for the diagnosis of acne vulgaris. Results: Repetitive measurements of the patients were interpreted with RCVs, after comparing the first and second doses based on RCVs: TC, TG, AST and ALT results increased in 12%, 20%, 14% and 12% of the patients respectively. When the first dose was compared with the last dose, the increases were 20%, 29%, 22% and 18% respectively interpreted as significant changes based on laboratory medicine. Conclusions: A more sensitive follow-up is possible in the monitorization of adverse effects by using RCVs method.en_US
dc.identifier.doi10.1093/labmed/lmw024
dc.identifier.endpage219en_US
dc.identifier.issn0007-5027
dc.identifier.issn1943-7730
dc.identifier.issue3en_US
dc.identifier.pmid27346869en_US
dc.identifier.scopus2-s2.0-85014503557en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage213en_US
dc.identifier.urihttps://doi.org/10.1093/labmed/lmw024
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8731
dc.identifier.volume47en_US
dc.identifier.wosWOS:000381879800008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBuğdaycı, Güler
dc.institutionauthorPolat, Mualla
dc.institutionauthorOğuzman, Hamdi
dc.institutionauthorÇinpolat, Havva Yasemin
dc.language.isoenen_US
dc.publisherOxford Univ Pressen_US
dc.relation.ispartofLaboratory Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectIsotretinoinen_US
dc.subjectAcne Vulgarisen_US
dc.subjectReferences Valuesen_US
dc.subjectSide Effectsen_US
dc.subjectData Interpretationen_US
dc.subjectClinical Chemistry Testen_US
dc.titleInterpretation of biochemical tests using the reference change value in monitoring adverse effects of oral isotretinoin in 102 ethnic Turkish patientsen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
lmw024.pdf
Boyut:
232.71 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin/Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Dahili Tıp Bilimleri Bölümü Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Temel Tıp Bilimleri Bölümü Koleksiyonu