Mean platelet volume: An overlooked herald of malignant thyroid nodules

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dc.authorid0000-0001-7306-5233en_US
dc.authorid0000-0002-4326-2102
dc.authorid0000-0002-7475-7298
dc.authorid0000-0003-4419-409X
dc.authorid0000-0002-7821-8275
dc.authorid0000-0002-1426-0247
dc.contributor.authorŞit, Mustafa
dc.contributor.authorAktaş, Gülali
dc.contributor.authorÖzer, Bahri
dc.contributor.authorKoçak, Mehmet Zahid
dc.contributor.authorErkuş, Edip
dc.contributor.authorErkol, Mehmet Hayri
dc.contributor.authorYaman, Semih
dc.date.accessioned2021-06-23T19:50:54Z
dc.date.available2021-06-23T19:50:54Z
dc.date.issued2019
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractPhysicians and surgeons pay much attention to evaluating thyroid nodules due to the malignant potential of these growths. Inflammation has a crucial role in the development of cancer. Increase in the mean platelet volume (MPV) has been described in various inflammatory conditions. Since some of thyroid nodules are malignant, we aimed to compare MPV values between patients with malignant and benign thyroid nodules after precise pathologic diagnosis. We retrospectively analyzed hemograms of patients having undergone thyroid surgery for thyroid nodule between January 2013 and January 2015, and compared them to those recorded in healthy subjects. MPV was higher in the malignant thyroid nodule group than in the benign nodule group (9.1 +/- 1 fL vs. 7.8 +/- 0.8 fL). The difference was statistically significant (p<0.001). Increased MPV should be considered as an assistive diagnostic tool in differentiating malignant and benign thyroid nodules. However, further prospective studies are required to confirm its usefulness in this population.en_US
dc.identifier.doi10.20471/acc.2019.58.03.03
dc.identifier.endpage420en_US
dc.identifier.issn0353-9466
dc.identifier.issn1333-9451
dc.identifier.issue3en_US
dc.identifier.pmid31969752en_US
dc.identifier.scopus2-s2.0-85083642797en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage417en_US
dc.identifier.urihttps://doi.org/10.20471/acc.2019.58.03.03
dc.identifier.urihttps://hdl.handle.net/20.500.12491/9883
dc.identifier.volume58en_US
dc.identifier.wosWOS:000503863900003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorŞit, Mustafa
dc.institutionauthorAktaş, Gülali
dc.institutionauthorÖzer, Bahri
dc.institutionauthorKoçak, Mehmet Zahid
dc.institutionauthorErkol, Mehmet Hayri
dc.language.isoenen_US
dc.publisherSestre Milosrdnice Univ Hospitalen_US
dc.relation.ispartofActa Clinica Croaticaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectThyroid Noduleen_US
dc.subjectNeoplasmsen_US
dc.subjectInflammationen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectBlood Cell Counten_US
dc.titleMean platelet volume: An overlooked herald of malignant thyroid nodulesen_US
dc.typeArticleen_US

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