Can bone quality be predicted accurately by Singh Index in patients with rheumatoid arthritis?

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dc.authorid0000-0003-1710-7018en_US
dc.contributor.authorBes, Cemal
dc.contributor.authorGüven, Melih
dc.contributor.authorAkman, Budak
dc.contributor.authorAtay, Evren Fehmi
dc.contributor.authorCeviz, Emrah
dc.contributor.authorSoy, Mehmet
dc.date.accessioned2021-06-23T19:34:01Z
dc.date.available2021-06-23T19:34:01Z
dc.date.issued2012
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractThe aim of this study was to evaluate Singh index as a simple and inexpensive means of estimation of bone quality in patients with rheumatoid arthritis. Singh index evaluation was made on digital pelvis radiographs in 50 consecutive patients by three observers. Bone mineral density T scores of the spine and left proximal femur were assessed using dual energy X-ray absorptiometry. Singh index was correlated with densitometry measurements after grouping the patients as normal, osteopenia and osteoporosis. Intra-and interobserver agreements were evaluated by kappa correlations. Sensitivity, specificity, positive and negative predictive values and likelihood ratio's of Singh index were calculated. Both intra-and interobserver agreements were 0.71 (range, 0.69 to 0.72) on average. Singh index proved highly sensitive for the diagnosis of osteopenia at the proximal femur (91%) and spine (90%), whereas the specificity of Singh index for identifying of osteoporosis at the femoral neck (93%) and spine (91%) was higher than sensitivity. Predictive values for osteoporosis at the proximal femur and spine were acceptable and positive likelihood ratios of Singh index for osteopenia and osteoporosis at the proximal femur were 2.4 and 10.1, respectively. Singh index can identify osteoporosis with a high specificity in patients with rheumatoid arthritis. However, the patients who are graded as osteopenia by the Singh index should undergo further evaluation with dual energy X-ray absorptiometry.en_US
dc.identifier.doi10.1007/s10067-011-1786-2
dc.identifier.endpage89en_US
dc.identifier.issn0770-3198
dc.identifier.issue1en_US
dc.identifier.pmid21655937en_US
dc.identifier.scopus2-s2.0-84856762523en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage85en_US
dc.identifier.urihttps://doi.org/10.1007/s10067-011-1786-2
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7342
dc.identifier.volume31en_US
dc.identifier.wosWOS:000299768200012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBes, Cemal
dc.institutionauthorSoy, Mehmet
dc.institutionauthorCeviz, Emrah
dc.language.isoenen_US
dc.publisherSpringer London Ltden_US
dc.relation.ispartofClinical Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBone Mineral Densityen_US
dc.subjectOsteopeniaen_US
dc.subjectOsteoporosisen_US
dc.subjectRheumatoid Arthritisen_US
dc.subjectSingh Indexen_US
dc.titleCan bone quality be predicted accurately by Singh Index in patients with rheumatoid arthritis?en_US
dc.typeArticleen_US

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