Elevated neutrophil-to-lymphocyte ratio in the diagnosis of Hashimoto's thyroiditis

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dc.authorid0000-0001-7306-5233en_US
dc.authorid0000-0002-7475-7298
dc.authorid0000-0001-9875-6065
dc.authorid0000-0002-1426-0247
dc.contributor.authorAktaş, Gülali
dc.contributor.authorŞit, Mustafa
dc.contributor.authorDikbaş, Oğuz
dc.contributor.authorErkol, Hayri
dc.contributor.authorAltınordu, Rabia
dc.contributor.authorErkuş, Edip
dc.contributor.authorŞavlı, Haluk
dc.date.accessioned2021-06-23T19:45:05Z
dc.date.available2021-06-23T19:45:05Z
dc.date.issued2017
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: Hashimoto's thyroiditis (HT) is an autoimmune inflammatory disorder. The purpose of this study was to determine the neutrophil-to-lymphocyte ratio (NLR), a novel marker of inflammation, in patients with HT and to compare these values with those from healthy subjects. Method: A total of 154 participants were included in the study, 90 HT patients and 64 healthy volunteers. Retrospectively, demographic and laboratory data of the subjects were obtained from our institution's database. Patients with active infection, diabetes mellitus, malignancy, other chronic inflammatory diseases, hematologic disorders and patients on aspirin or steroid treatment were excluded from the study. Values for complete blood count (CBC) and serum laboratory parameters of HT patients were the baseline values obtained at the time of HT diagnosis. Control subjects consisted of healthy volunteers who visited our institution for a routine check-up. Results: Age, gender and CBC parameters were not different between the HT group and the control group; however, the NLR of HT group (2.1 [1.3-5.8]) was significantly higher than the control group (1.9 [0.6-3.3]), p=0.04. Conclusion: Increased NLR may be useful as an indicator of the presence of HT, especially in complicated cases. NLR is inexpensive and easy to determine. Larger, prospective studies are required to determine its usefulness in assessing diagnostic potential and treatment outcomes in HT patients.en_US
dc.identifier.doi10.1590/1806-9282.63.12.1065
dc.identifier.endpage1068en_US
dc.identifier.issn1806-9282
dc.identifier.issue12en_US
dc.identifier.pmid29489971en_US
dc.identifier.scopus2-s2.0-85042696155en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1065en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/9097
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:000426268800011
dc.identifier.volume63en_US
dc.identifier.wosWOS:000426268800011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAktaş, Gülali
dc.institutionauthorŞit, Mustafa
dc.institutionauthorErkol, Hayri
dc.institutionauthorAltınordu, Rabia
dc.institutionauthorErkuş, Edip
dc.institutionauthorŞavlı, Haluk
dc.language.isoenen_US
dc.publisherAssoc Medica Brasileiraen_US
dc.relation.ispartofRevista Da Associacao Medica Brasileiraen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHashimoto Diseaseen_US
dc.subjectBlood Cell Counten_US
dc.subjectInflammationen_US
dc.subjectDiagnosisen_US
dc.titleElevated neutrophil-to-lymphocyte ratio in the diagnosis of Hashimoto's thyroiditisen_US
dc.typeArticleen_US

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