Contractile responses of rabbit bladder neck to adrenaline, acetylcholine and papaverine after doxazosin treatment

dc.authorid0000-0001-8688-4772en_US
dc.authorid0000-0002-3630-7982en_US
dc.contributor.authorEroğlu, Muzaffer
dc.contributor.authorSezgin, Aysun
dc.contributor.authorSemerciöz, Atilla
dc.contributor.authorMetin, Ahmet
dc.contributor.authorKandıralı, Engin
dc.contributor.authorOnur, M. Ali
dc.date.accessioned2021-06-23T19:20:24Z
dc.date.available2021-06-23T19:20:24Z
dc.date.issued2007
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractIt has been demonstrated that long-term administration of doxazosin, an alpha 1 adrenoceptor antagonist, causes an up-regulation in the expression of alpha 1 adrenoceptor subtype mRNAs in the rat genitourinary tract. The aim of this study is to determine whether this up-regulation does have any effect on contractile response of rabbit bladder neck to adrenaline, acethylcholine and papaverin after long-term doxazosin treatment. Fourteen rabbits, treated with doxazosin 3 mg/kg/day p.o for 6 months, and were fed with a diet of standard laboratory rabbit chow (100 g/kg/day). Ten rabbits received the same amount of regular chow but no drug. Contractile responses of rabbit bladder neck to adrenaline acethylcholine and papaverine were measured.en_US
dc.identifier.doi10.1007/s11255-006-9047-z
dc.identifier.endpage141en_US
dc.identifier.issn0301-1623
dc.identifier.issue1en_US
dc.identifier.pmid17171413en_US
dc.identifier.scopus2-s2.0-34248231308en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage137en_US
dc.identifier.urihttps://doi.org/10.1007/s11255-006-9047-z
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6109
dc.identifier.volume39en_US
dc.identifier.wosWOS:000246203900030en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorEroğlu, Muzaffer
dc.institutionauthorSemerciöz, Atilla
dc.institutionauthorMetin, Ahmet
dc.institutionauthorKandıralı, Engin
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Urology And Nephrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcetylcholineen_US
dc.subjectAdrenalineen_US
dc.subjectBladder necken_US
dc.subjectContractionen_US
dc.subjectPapaverineen_US
dc.titleContractile responses of rabbit bladder neck to adrenaline, acetylcholine and papaverine after doxazosin treatmenten_US
dc.typeArticleen_US

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