Comparison of ocular surface side effects of topical travoprost and bimatoprost

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dc.authorid0000-0002-0184-8033en_US
dc.authorid0000-0003-4096-4261
dc.contributor.authorAlagöz, Gürsoy
dc.contributor.authorBayer, Atilla
dc.contributor.authorBoran, Çetin
dc.contributor.authorSerin, Didem
dc.contributor.authorKükner, Aysel
dc.contributor.authorElçioğlu, Mustafa
dc.date.accessioned2021-06-23T19:26:00Z
dc.date.available2021-06-23T19:26:00Z
dc.date.issued2008
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü
dc.description1st World Glaucoma Congress -- JUL 06-09, 2005 -- Vienna, AUSTRIAen_US
dc.description.abstractPurpose: To compare the subjective symptoms, conjunctival hyperemia, tearing response and conjunctival cytological changes secondary to topical administration of bimatoprost and travoprost for 6 months. Methods: Newly diagnosed primary open-angle glaucoma patients were randomly prescribed bimatoprost (35 cases) or travoprost (42 cases). Two patients in each group were excluded because they did not appear at their appointments regularly. Thus, 33 and 40 patients completed the study in the bimatoprost and travoprost groups, respectively. Redness, itching, foreign-body sensation, pain and discomfort were assessed by a questionnaire, and patients were examined for conjunctival hyperemia. Schirmer's I and break-up time tests were performed, and impression cytology of conjunctiva was evaluated. Results: Subjective symptoms were similar in both groups. The only subjective symptom that changed significantly was redness. The change in conjunctival hyperemia along the study period correlated with the patient-reported redness in both groups, being highest on day 30. Schirmer's test I and break-up time did not change with time and were similar in both groups. The impression cytology grade increased with time in both groups with the only significant difference between groups on day 90 (higher in the bimatoprost group). Conclusion: We observed conjunctival hyperemia as the most common side effect of bimatoprost and travoprost. Tear film functions were not affected by these drugs while cytological alterations were. Copyright (C) 2008 S. Karger AG, Basel.en_US
dc.description.sponsorshipAssoc Int Glaucoma Socen_US
dc.identifier.doi10.1159/000126078
dc.identifier.endpage167en_US
dc.identifier.issn0030-3755
dc.identifier.issn1423-0267
dc.identifier.issue3en_US
dc.identifier.pmid18497524en_US
dc.identifier.scopus2-s2.0-44349151702en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage161en_US
dc.identifier.urihttps://doi.org/10.1159/000126078
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6371
dc.identifier.volume222en_US
dc.identifier.wosWOS:000256353500005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAlagöz, Gürsoy
dc.institutionauthorBoran, Çetin
dc.institutionauthorSerin, Didem
dc.institutionauthorKükner, Aysel
dc.institutionauthorElçioğlu, Mustafa
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofOphthalmologicaen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGlaucomaen_US
dc.subjectTravoprosten_US
dc.subjectBimatoprosten_US
dc.subjectTear Filmen_US
dc.titleComparison of ocular surface side effects of topical travoprost and bimatoprosten_US
dc.typeConference Objecten_US

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