Diagnostic and prognostic importance of the neutrophil lymphocyte ratio in breast cancer

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dc.authorid0000-0001-6966-9149en_US
dc.authorid0000-0001-8590-4831
dc.authorid0000-0002-0545-0110
dc.authorid0000-0002-5489-2222
dc.contributor.authorÖzyalvaçlı, Gülzade
dc.contributor.authorYeşil, Cemile
dc.contributor.authorKargı, Ertuğrul
dc.contributor.authorKızıldağ, Betül
dc.contributor.authorKilitçi, Asuman
dc.contributor.authorYılmaz, Fahri
dc.date.accessioned2021-06-23T19:36:32Z
dc.date.available2021-06-23T19:36:32Z
dc.date.issued2014
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: The aim of this study was to determine diagnostic and prognostic roles of the neutrophil to lymphocyte ratio (NLR) in breast cancer patients. To date, data are limited on associations of primary breast carcinoma (PBC) and benign proliferative breast disease (BPBD) with preoperative NLR values. Materials and Methods: Our study covered of 120 female patients with PBC and 50 with BPBD. Diagnostic values of NLR were estimated using sensitivity, specificity and areas under receiver operating characteristic curves (AUC). Results: NLR values were significantly higher in the PBC patients than in those with BPBD, with an AUC of 0.668 in the PBC case. The optimal cut-off for NLR was 2.96 and this was validated in the testing set, giving a sensitivity and a specificity of 79.7% and 76.2%, respectively, in PBC patients. Conclusions: Preoperative high NLR is a significant diagnostic predictor of distinction of breast cancer from BPBD and elevated NLR is also an important prognostic marker for primary invasive breast cancer.en_US
dc.identifier.doi10.7314/APJCP.2014.15.23.10363
dc.identifier.endpage10366en_US
dc.identifier.issn1513-7368
dc.identifier.issue23en_US
dc.identifier.pmid25556476en_US
dc.identifier.scopus2-s2.0-84921751819en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage10363en_US
dc.identifier.urihttps://doi.org/10.7314/APJCP.2014.15.23.10363
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8011
dc.identifier.volume15en_US
dc.identifier.wosWOS:000351058400054en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÖzyalvaçlı, Gülzade
dc.institutionauthorKargı, Ertuğrul
dc.institutionauthorKızıldağ, Betül
dc.institutionauthorKilitçi, Asuman
dc.institutionauthorYılmaz, Fahri
dc.language.isoenen_US
dc.publisherAsian Pacific Organization Cancer Preventionen_US
dc.relation.ispartofAsian Pacific Journal Of Cancer Preventionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBreast Carcinomaen_US
dc.subjectNeutrophilen_US
dc.subjectLymphocyteen_US
dc.subjectRationen_US
dc.subjectDiagnosisen_US
dc.subjectPrognosisen_US
dc.titleDiagnostic and prognostic importance of the neutrophil lymphocyte ratio in breast canceren_US
dc.typeArticleen_US

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