Neutrophil to lymphocyte ratio is useful in differentiation of malign and benign thyroid nodules

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dc.authorid0000-0001-7306-5233en_US
dc.authorid0000-0002-7475-7298
dc.authorid0000-0002-1426-0247
dc.contributor.authorŞit, Mustafa
dc.contributor.authorAktaş, Gülali
dc.contributor.authorErkol, Mehmet Hayri
dc.contributor.authorYaman, Semih
dc.contributor.authorKeyif, Fatih
dc.contributor.authorŞavlı, Haluk
dc.date.accessioned2021-06-23T19:52:09Z
dc.date.available2021-06-23T19:52:09Z
dc.date.issued2019
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: Significant amount of thyroid nodules are malignant. Inflammation plays crucial role in the pathogenesis of many disorders, including cancer. Neutrophil to lymphocyte ratio (NLR), has been suggested as an index of inflammatory response and association between increased NLR and cancer has also been reported. In this retrospective analysis, we aimed to study NLR levels in patients with malign and benign thyroid nodules and healthy control subjects. Methods: The patients who underwent surgery for nodular goiter in general surgery clinics of our university hospital between June 2012 and June 2015 and 68 healthy volunteers were included. Patients with thyroid nodules divided into malign or benign nodule groups according to the pathology report. Thyroid carcinomas other than micropapillary tumor were excluded. Preoperative hemogram parameters of these groups were compared. Results: Mean NLR of malign nodule group (2.1 +/- 0.9%) was significantly higher than both those in benign nodule (1.7 +/- 0.9%) and control groups (1.7 +/- 0.6%). Conclusion: We suggest that elevated NLR in patients with thyroid nodules in preoperative period may be an indicator of underlying malign nodular disease. Increased NLR in such patients should encourage physician to perform cancer screening in thyroid gland.en_US
dc.identifier.endpage63en_US
dc.identifier.issn0738-0658
dc.identifier.issue1en_US
dc.identifier.pmid30924917en_US
dc.identifier.scopus2-s2.0-85064139794en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage60en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10105
dc.identifier.urihttps://prhsj.rcm.upr.edu/index.php/prhsj/article/view/1828
dc.identifier.volume38en_US
dc.identifier.wosWOS:000461958400010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorŞavlı, Haluk
dc.institutionauthorŞit, Mustafa
dc.institutionauthorAktaş, Gülali
dc.institutionauthorErkol, Mehmet Hayri
dc.language.isoenen_US
dc.publisherUniv Puerto Rico Medical Sciences Campusen_US
dc.relation.ispartofPuerto Rico Health Sciences Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNeutrophil to Lymphocyte Ratioen_US
dc.subjectInflammationen_US
dc.subjectThyroid Noduleen_US
dc.subjectCanceren_US
dc.titleNeutrophil to lymphocyte ratio is useful in differentiation of malign and benign thyroid nodulesen_US
dc.typeArticleen_US

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