Neutrophil to lymphocyte ratio is useful in differentiation of malign and benign thyroid nodules
Yükleniyor...
Dosyalar
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Univ Puerto Rico Medical Sciences Campus
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: Significant amount of thyroid nodules are malignant. Inflammation plays crucial role in the pathogenesis of many disorders, including cancer. Neutrophil to lymphocyte ratio (NLR), has been suggested as an index of inflammatory response and association between increased NLR and cancer has also been reported. In this retrospective analysis, we aimed to study NLR levels in patients with malign and benign thyroid nodules and healthy control subjects. Methods: The patients who underwent surgery for nodular goiter in general surgery clinics of our university hospital between June 2012 and June 2015 and 68 healthy volunteers were included. Patients with thyroid nodules divided into malign or benign nodule groups according to the pathology report. Thyroid carcinomas other than micropapillary tumor were excluded. Preoperative hemogram parameters of these groups were compared. Results: Mean NLR of malign nodule group (2.1 +/- 0.9%) was significantly higher than both those in benign nodule (1.7 +/- 0.9%) and control groups (1.7 +/- 0.6%). Conclusion: We suggest that elevated NLR in patients with thyroid nodules in preoperative period may be an indicator of underlying malign nodular disease. Increased NLR in such patients should encourage physician to perform cancer screening in thyroid gland.
Açıklama
Anahtar Kelimeler
Neutrophil to Lymphocyte Ratio, Inflammation, Thyroid Nodule, Cancer
Kaynak
Puerto Rico Health Sciences Journal
WoS Q Değeri
Q4
Scopus Q Değeri
Q4
Cilt
38
Sayı
1
