Effects of iohexol on ventilatory functions in patients undergoing diagnostic coronary angiography

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dc.authorid0000-0002-2262-3087
dc.authorid0000-0002-7413-1367
dc.authorid0000-0001-5730-0790
dc.authorid0000-0003-2541-4675
dc.authorid0000-0002-8877-3520
dc.contributor.authorÖzhan, Hakan
dc.contributor.authorAkdemir, Ramazan
dc.contributor.authorBalbay, Öner
dc.contributor.authorArbak, Peri
dc.contributor.authorErbaş, Mete
dc.contributor.authorGündüz, Hüseyin
dc.contributor.authorYazıcı, Mehmet
dc.contributor.authorErbilen, Enver
dc.contributor.authorUyan, Cihangir
dc.date.accessioned2021-06-23T19:17:46Z
dc.date.available2021-06-23T19:17:46Z
dc.date.issued2004
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground and objectives Adverse respiratory reactions have been reported with intravascular radiographic contrast media. The aim of the present study is to assess the effects of iohexol on pulmonary functions in patients undergoing diagnostic coronary angiography (CA). Materials and methods: 30 patients enrolled in the study. The respiratory functions of the patients were measured at three different stages during angiography (before, immediately after and 2 h later) and arterial blood gas analyses were performed at six stages during CA (before, immediately after the insertion of angiography catheter, 2 min after the injection of contrast agent, at the end of angiography, an hour and 2 h after angiography). A single, experienced angiographer performed the angiography procedures via radial artery route. Totally six multiple angled views of the left and right coronary arteries were recorded in all patients by hand injection. None of the patients were performed ventriculography. Results: Angiography caused significant reduction in forced expiratory volume in 1 sec [FEV1] (from 103 15 to 95 17, p < 0.01), forced vital capacity [FVC] (from 99 13 to 95 18, p < 0.05) and maximum mid-expiratory flow rate [MMF] (from 95 33 to 84 29, p < 0.01) whereas there were no significant changes in the mean FEV1/FVC ratios at different stages of angiography. Statistically significant decrease in PaO2 (from 91 10 to 85 13 mmHg, p < 0.01) and arterial O2 saturation (from 97 1% to 96 1%, p < 0.01) were also observed. Data in present study showed a clinically insignificant but statistically significant restrictive impairment in pulmonary functions. Conclusions: Diagnostic CA using iohexol decreases ventilatory functions in a small but significant extent in patients without any overt pulmonary disease.en_US
dc.identifier.doi10.1007/s10554-004-1094-x
dc.identifier.endpage470en_US
dc.identifier.issn1569-5794
dc.identifier.issue6en_US
dc.identifier.pmid15856627en_US
dc.identifier.scopus2-s2.0-14944380567en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage465en_US
dc.identifier.urihttps://doi.org/10.1007/s10554-004-1094-x
dc.identifier.urihttps://hdl.handle.net/20.500.12491/5540
dc.identifier.volume20en_US
dc.identifier.wosWOS:000227364200001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÖzhan, Hakan
dc.institutionauthorAkdemir, Ramazan
dc.institutionauthorBalbay, Öner
dc.institutionauthorArbak, Peri
dc.institutionauthorErbaş, Mete
dc.institutionauthorGündüz, Hüseyin
dc.institutionauthorYazıcı, Mehmet
dc.institutionauthorErbilen, Enver
dc.institutionauthorUyan, Cihangir
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Journal Of Cardiovascular Imagingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCoronary Angiographyen_US
dc.subjectIohexolen_US
dc.subjectVentilatory Functionen_US
dc.titleEffects of iohexol on ventilatory functions in patients undergoing diagnostic coronary angiographyen_US
dc.typeArticleen_US

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