Optical coherence tomography findings in Parkinson's disease

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dc.authorid0000-0003-4468-3985en_US
dc.authorid0000-0001-8616-832X
dc.authorid0000-0002-8249-2621
dc.authorid0000-0001-5524-5767
dc.authorid0000-0002-9647-4432
dc.contributor.authorTürkoğlu, Şule Aydın
dc.contributor.authorÜmit, Doğan
dc.contributor.authorÖgün, Muhammed Nur
dc.contributor.authorUlaş, Fatih
dc.contributor.authorKeleş, Asena
dc.contributor.authorYavaş, Nefise Öztürk
dc.contributor.authorYıldız, Serpil
dc.date.accessioned2021-06-23T19:49:54Z
dc.date.available2021-06-23T19:49:54Z
dc.date.issued2018
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractThe aim of this study is to compare optical coherence tomography (OCT) findings of retinal thickness (RT) and retinal nerve fiber layer thickness (RNFLT) of idiopathic Parkinson's disease (IPD) patients to those of healthy subjects, and to investigate whether there is any relationship between the severity of the disease and the RNFLT values. This prospective study was included 25 IPD patients and 29 healthy controls. In the IPD group, the Hoehn and Yahr (H&Y), Unified Parkinson's Disease Rating Scale (UPDRS), and Mini-Mental State Exam (MMSE) were performed. Intraocular pressure (IOP), visual acuity (VA), spherical equivalent, axial length (AL), and central corneal thickness (CCT) were measured using OCT in both groups. The RT was measured in the central retinal (RTc), nasal (RTn), and temporal (RTt) segments. Nasal (RNFLTn), nasal superior (RNFLTns), nasal inferior (RNFLTni), temporal (RNFLTt), temporal superior (RNFLTts), and temporal inferior (RNFLTti) measurements were made and mean RTFLT was calculated (RNFLTg) for each individual. In the patient group, IOP and VA values were statistically significantly lower The RTn and RNFLTg were significantly thinner in the patient group. There was no statistically significant relationship between the severity of IPD and these findings. In our study, RNFLTg and RTn were found to be thinner in the IPD group, which may have caused lower VA scores. The effects of retinal dopamine depletion on RT and RNFLT, and lower IOP values in the non-glaucomatous IPD patients should be further investigated. Copyright (C) 2017, Kaohsiung Medical University. Published by Elsevier Taiwan LLC.en_US
dc.identifier.doi10.1016/j.kjms.2017.11.006
dc.identifier.endpage171en_US
dc.identifier.issn1607-551X
dc.identifier.issn2410-8650
dc.identifier.issue3en_US
dc.identifier.pmid29475464en_US
dc.identifier.scopus2-s2.0-85042292876en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage166en_US
dc.identifier.urihttps://doi.org/10.1016/j.kjms.2017.11.006
dc.identifier.urihttps://hdl.handle.net/20.500.12491/9649
dc.identifier.volume34en_US
dc.identifier.wosWOS:000426072700006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorTürkoğlu, Şule Aydın
dc.institutionauthorÖgün, Muhammed Nur
dc.institutionauthorÜmit, Doğan
dc.institutionauthorYıldız, Serpil
dc.institutionauthorUlaş, Fatih
dc.institutionauthorKeleş, Asena
dc.institutionauthorYavaş, Nefise Öztürk
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofKaohsiung Journal Of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectParkinson's Diseaseen_US
dc.subjectCoherence Tomographyen_US
dc.subjectOpticalen_US
dc.titleOptical coherence tomography findings in Parkinson's diseaseen_US
dc.typeArticleen_US

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