Factors affecting the levels of red cell distribution width
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Tarih
2015
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Verduci Publisher
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Dear Editor,
We thank to the authors for their valuable comments about our study1. They emphasized that elevated red cell distribution width (RDW) helps to early diagnosis of nutritional deficiency of iron, folic acid and vitamin B12. Also they pointed to elevated RDW could be
associated with sickle cell anemia, hemolytic anemia, chronic liver disease and myelodysplastic syndrome.
Possible causes of high RDW levels can be determined by comparison with mean corpuscular
volume (MCV). The MCV is the average amount of space occupied by each red blood cell. If both the RDW and MCV levels are increased, there are several possible causes such as liver disease, hemolytic anemia and vitamin B12 or folic acid deficiency. Another condition is the combination of
high RDW levels with low MCV levels. This may be resulted from iron deficiency anemia or thalessemia intermedia. In our study, the patient groups did not have nutritional anemias according to their MCV levels were in normal range for their age groups (6 months up to 6 years old)2. Also, due to retrospective nature of our study, it is not possible to investigate ferritin, folic acid and vitamin B12 levels of the patients.
Açıklama
Anahtar Kelimeler
Red Cell Distribution Width, Red Cell, Vitamin B12, RDW, MCV Levels
Kaynak
European Review For Medical And Pharmacological Sciences
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
19
Sayı
3
