Serum cardiotrophin-1 and IL-6 Levels in patients with obstructive sleep apnea syndrome

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dc.authorid0000-0002-4641-2866en_US
dc.contributor.authorKurt, Özlem Kar
dc.contributor.authorTosun, Mehmet
dc.contributor.authorTalay, Fahrettin
dc.date.accessioned2021-06-23T19:34:07Z
dc.date.available2021-06-23T19:34:07Z
dc.date.issued2013
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractObstructive sleep apnea syndrome (OSAS) is associated with increased rates of cardiovascular diseases (CVD). Basic mechanisms involved in the increased cardiovascular risk of OSAS remain unclear. Inflammation has been shown to potentially play a critical role in this association. The aim of the present study was to investigate the level of cardiotrophin-1 (CT-1) in patients with OSAS. Forty-eight newly diagnosed OSAS patients and 37 nonapneic controls were enrolled in this study. Demographic data, cigarette smoking status, previous history of chronic diseases including CVD and metabolic diseases and drugs, and habits were obtained by a standardized questionnaire. All patients underwent polysomnographic evaluation. The mean age was 48.3 +/- 12.3 (24-74) years in OSAS group. Median apnea-hypopnea index was 23.6 (6-91.8) and median body mass index was 30.4 (24.2-49.4) in the OSAS group. Plasma CT-1 levels in OSAS and control groups, respectively, were 12.03 +/- 1.08 and 11.85 +/- 1.18 pg/ml. There was no significant difference in the plasma levels of CT-1 and IL-6 between the OSAS group and the controls.en_US
dc.identifier.doi10.1007/s10753-013-9673-4
dc.identifier.endpage1347en_US
dc.identifier.issn0360-3997
dc.identifier.issn1573-2576
dc.identifier.issue6en_US
dc.identifier.pmid23783568en_US
dc.identifier.scopus2-s2.0-84888204516en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1344en_US
dc.identifier.urihttps://doi.org/10.1007/s10753-013-9673-4
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7386
dc.identifier.volume36en_US
dc.identifier.wosWOS:000326692200019en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKurt, Özlem Kar
dc.institutionauthorTosun, Mehmet
dc.institutionauthorTalay, Fahrettin
dc.language.isoenen_US
dc.publisherSpringer/Plenum Publishersen_US
dc.relation.ispartofInflammationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCardiotrophin-1en_US
dc.subjectInterleukin-6en_US
dc.subjectObstructive Sleep Apnea Syndromeen_US
dc.subjectInflammationen_US
dc.titleSerum cardiotrophin-1 and IL-6 Levels in patients with obstructive sleep apnea syndromeen_US
dc.typeArticleen_US

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