Impression cytology of the ocular surface and tear function in patients with periocular vitiligo

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dc.authorid0000-0002-4447-756X
dc.authorid0000-0003-4096-4261
dc.contributor.authorSerin, Didem
dc.contributor.authorButtanrı, İbrahim Bülent
dc.contributor.authorParlak, Ali Haydar
dc.contributor.authorBoran, Çetin
dc.contributor.authorTırak, Erkan
dc.date.accessioned2021-06-23T19:29:13Z
dc.date.available2021-06-23T19:29:13Z
dc.date.issued2012
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractPURPOSE. We evaluated the ocular surface and tear function in patients with periocular vitiligo in this prospective, case-control study. METHODS. Sixty eyes of 30 vitiligo patients with periocular involvement and 100 eyes of 50 control subjects were included in the study. Patients and control subjects were compared for Schirmer test and tear film break-up time (BUT) results and impression cytology findings graded according to Nelson's classification. RESULTS. The mean BUT value was 9.5 +/- 4.1 seconds in patients with periocular vitiligo and 13.1 +/- 4.2 seconds in the control group. The difference was statistically significant (p=0.005). Thirty-seven eyes (61.7%) in the vitiligo group and 28 eyes (28.0%) in the control group had BUT values less than 10 seconds (p<0.001). The mean Schirmer test value was 14.6 +/- 4.3 mm in patients with periocular vitiligo and 15.1 +/- 4.4 mm in the control group (p>0.05). Nineteen eyes (31.7%) in patients with periocular vitiligo and 8 eyes (8.0%) in the control group had grade 2-3 changes according to Nelson's classification (p<0.001). Three eyes (5.0%) in the periocular vitiligo group and none of the eyes in the control group had inflammation signs in the impression cytology analysis. CONCLUSIONS. In patients with periocular vitiligo, ocular surface and tear function alterations may occur. Further studies on ocular surface involvement in periocular vitiligo patients may help to increase understanding of the pathophysiology of vitiligo.en_US
dc.identifier.doi10.5301/ejo.5000099
dc.identifier.endpage738en_US
dc.identifier.issn1120-6721
dc.identifier.issue5en_US
dc.identifier.pmid22267461en_US
dc.identifier.scopus2-s2.0-84864927755en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage734en_US
dc.identifier.urihttps://doi.org/10.5301/ejo.5000099
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7136
dc.identifier.volume22en_US
dc.identifier.wosWOS:000310177100009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorParlak, Ali Haydar
dc.language.isoenen_US
dc.publisherWichtig Editoreen_US
dc.relation.ispartofEuropean Journal Of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectImpression Cytologyen_US
dc.subjectTear Functionen_US
dc.subjectVitiligoen_US
dc.titleImpression cytology of the ocular surface and tear function in patients with periocular vitiligoen_US
dc.typeArticleen_US

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