Serum levels of omentin in end-stage renal disease patients

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dc.authorid0000-0002-3156-1076en_US
dc.authorid0000-0002-7526-7151en_US
dc.authorid0000-0001-7306-5233en_US
dc.authorid0000-0003-1698-8263
dc.contributor.authorAlçelik, Aytekin
dc.contributor.authorTosun, Mehmet
dc.contributor.authorÖzlü, Mehmet Fatih
dc.contributor.authorEroğlu, Mustafa
dc.contributor.authorAktaş, Gülali
dc.contributor.authorKemahlı, Eray
dc.contributor.authorŞavlı, Haluk
dc.date.accessioned2021-06-23T19:33:56Z
dc.date.available2021-06-23T19:33:56Z
dc.date.issued2012
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractIntroduction: Cardiovascular disease is the leading cause of morbidity and mortality in hemodialysis patients. Therefore, evaluation and prevention of cardiovascular diseases in end-stage renal disease (ESRD) patients are very important. The plasma level of omentin was found to be associated with different conditions such as insulin resistance. It is one of the novel adipokines synthesized mainly in the visceral adipose tissue. In this study, we aimed to investigate the level of omentin in patients with ESRD receiving hemodialysis. Methods: The study population consisted of 59 adult chronic hemodialysis patients (30 women and 29 men) and age-matched control subjects were selected from apparently healthy subjects (28 participants; 14 women and 14 men). Blood samples were obtained before the dialysis session. Omentin concentrations were determined by using enzyme-linked immunosorbent assay. Results: Plasma levels of omentin were found to be markedly higher in ESRD patients (606.6 +/- 313.0 ng/ml) than in the control group (357.5 +/- 147.4 ng/ml; p < 0.0001). Also, serum omentin levels were found to be correlated with creatinine (r = 0.333, p = 0.002). Conclusions: Omentin levels were found to be elevated in patients with ESRD receiving hemodialysis. To the best of our knowledge, this is the first clinical study that demonstrated the association between omentin and ESRD. Copyright (C) 2012 S. Karger AG, Baselen_US
dc.identifier.doi10.1159/000338796
dc.identifier.endpage516en_US
dc.identifier.issn1420-4096
dc.identifier.issue6en_US
dc.identifier.pmid22813935en_US
dc.identifier.startpage511en_US
dc.identifier.urihttps://doi.org/10.1159/000338796
dc.identifier.urihttps://hdl.handle.net/20.500.12491/7290
dc.identifier.volume35en_US
dc.identifier.wosWOS:000314461100016en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAlçelik, Aytekin
dc.institutionauthorTosun, Mehmet
dc.institutionauthorÖzlü, Mehmet Fatih
dc.institutionauthorAktaş, Gülali
dc.institutionauthorKemahlı, Eray
dc.institutionauthorŞavlı, Haluk
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofKidney & Blood Pressure Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOmentinen_US
dc.subjectHemodialysisen_US
dc.subjectDiabetes Mellitusen_US
dc.subjectEnd-stage Renal Diseaseen_US
dc.titleSerum levels of omentin in end-stage renal disease patientsen_US
dc.typeArticleen_US

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