Helicobacter pylori infection in epileptic patients

dc.contributor.authorÖztürk, Ayhan
dc.contributor.authorÖztürk, C. Elif
dc.contributor.authorÖzdemirli, Burcu
dc.contributor.authorYücel, Muhterem
dc.contributor.authorBahçebaşı, Talat
dc.date.accessioned2021-06-23T19:20:27Z
dc.date.available2021-06-23T19:20:27Z
dc.date.issued2007
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü
dc.description.abstractIt is well known that there might be an epidemiological association between Helicobacter pylori infection and extraintestinal diseases. This study aimed at determining H. pylori infection in epileptic patients. Forty-seven cryptogenic epileptic patients (Group 1) and 35 healthy people (Group 2) participated in this study. Presence of H. pylori infection was examined by H. pylori stool antigen (HpSA), H. pylori IgG, and IgM. HpSA was detected in 21 participants (44.6%) in Group 1 and in 3 participants (8.5%) in Group 2. H. pylori IgM was positive in 27 participants (57.4%) in Group 1 and in 8 participants (22.8%) in Group 2. H. pylori IgG was positive in 37 participants (78.7%) in Group 1 and in 13 participants (38%) in Group 2. The difference of rates of HpSA, H. pylori IgM and IgG in Groups 1 and 2 were found statistically significant (chi(2) = 4.18, p = 0.04; chi(2) = 9.18, p = 0.0017; chi(2) = 14.58, p < 0.001, respectively). We also compared presence of H. pylori infection between the epileptic patients with poor and good prognosis; HpSA positivity was detected in 15 (62.5%) of 24 and 6 (26%) of 23, respectively, and the differences were statistically significant (chi(2) = 6.30, p = 0.012). H. pylori IgM positivity was detected in 16 (66%) of 24 patients with poor prognosis and 11 (47.8%) of 23 patients with good prognosis (p > 0.05). H. pylori IgG positivity was detected in 18 (75%) of 24 patients with poor prognosis and 19 (82.6%) of 23 patients with good prognosis. The differences of H. pylori IgM and IgG positivity rates in epileptic patients with poor and good prognosis were not found statistically significant (p > 0.05). These results suggest a probable association between the acute H. pylori infection and epilepsy, especially with poor prognosis. (C) 2006 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.seizure.2006.10.015
dc.identifier.endpage152en_US
dc.identifier.issn1059-1311
dc.identifier.issn1532-2688
dc.identifier.issue2en_US
dc.identifier.pmid17126040en_US
dc.identifier.scopus2-s2.0-33846846195en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage147en_US
dc.identifier.urihttps://doi.org/10.1016/j.seizure.2006.10.015
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6116
dc.identifier.volume16en_US
dc.identifier.wosWOS:000245320300008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÖztürk, Ayhan
dc.institutionauthorÖztürk, C. Elif
dc.institutionauthorÖzdemirli, Burcu
dc.institutionauthorYücel, Muhterem
dc.institutionauthorBahçebaşı, Talat
dc.language.isoenen_US
dc.publisherBEA Trading, Ltd. Allen_US
dc.relation.ispartofSeizure-European Journal Of Epilepsyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHelicobacter pylori infectionen_US
dc.subjectCryptogenic epilepsyen_US
dc.titleHelicobacter pylori infection in epileptic patientsen_US
dc.typeArticleen_US

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