C-reactive protein-to-serum albumin ratio as a marker of prognosis in adult intensive care population

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dc.authorid0000-0003-2954-4784en_US
dc.authorid0000-0003-1949-0890en_US
dc.authorid0000000243262102en_US
dc.contributor.authorKaragöz, İbrahim
dc.contributor.authorÖzer, Bahri
dc.contributor.authorİtal, Kasım İlker
dc.contributor.authorTürkoğlu, Mustafa
dc.contributor.authorDişikırık, Akın
dc.contributor.authorÖzer, Songül Peltek
dc.date.accessioned2023-08-14T09:56:23Z
dc.date.available2023-08-14T09:56:23Z
dc.date.issued2023en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractBACKGROUND: Patients in intensive care unit (ICU) require close follow up and clinical attention due to variability in the course of their underlying morbidities. The estimation of prognosis in these subjects has an utmost importance. Recent studies showed that C-reactive protein-to-serum albumin ratio (CAR) could be a reliable marker of inflammation in certain conditions. We aimed to compare CAR levels of deceased patients to those in survived subjects treated in ICU.PATIENTS AND METHODS: We retrospectively analyzed the data of adult patients. CAR was simply calculated by dividing the levels of CRP by those of serum albumin. Patients were grouped either as deceased or survived according to the prognosis. The data of the survived and deceased ICU subjects were compared.RESULTS: A total of 208 subjects, 101 deceased and 107 survived, were enrolled in the study. Median CAR levels of the deceased and survived subjects were 49.5 (3-153 %) and 11 (0.2-119 %), respectively (p < 0.001). CAR was significantly correlated with PDW (r = 0.24; p < 0.001) and serum creatinine (r = 0.27; p < 0.001) levels. In ROC analysis, CAR values higher than 30.2 % have 72 % sensitivity and 70 % specificity in predicting mortality in ICU population (AUC: 0.74; p < 0.001; 95% CI: 0.67-0.81).CONCLUSIONS: We suggest that CAR levels of the subjects in ICU should be evaluated during medical care. Increased CAR levels should alert physicians for a worse outcome in those subjects (Tab. 1, Fig. 1, Ref. 21). Text in PDF www.elis.sken_US
dc.identifier.citationKaragoz, I., Ozer, B., Ital, I., Turkoglu, M., Disikirik, A., & PELTEK OZER, S. (2023). C-reactive protein-to-serum albumin ratio as a marker of prognosis in adult intensive care population. Bratislava Medical Journal/Bratislavske Lekarske Listy, 124(4).en_US
dc.identifier.doi10.4149/BLL_2023_042
dc.identifier.endpage279en_US
dc.identifier.issn0006-9248
dc.identifier.issn1336-0345
dc.identifier.issue4en_US
dc.identifier.pmid36598321en_US
dc.identifier.scopus2-s2.0-85150000370en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage277en_US
dc.identifier.urihttp://dx.doi.org/10.4149/BLL_2023_042
dc.identifier.urihttps://hdl.handle.net/20.500.12491/11510
dc.identifier.volume124en_US
dc.identifier.wosWOS:000957700000005en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorKaragöz, İbrahim
dc.institutionauthorÖzer, Bahri
dc.institutionauthorİtal, Kasım İlker
dc.language.isoenen_US
dc.publisherAepress Sroen_US
dc.relation.ispartofBratislava Medical Journal-Bratislavske Lekarske Listyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectC-Reactive Protein-To-Serum Albumin Ratioen_US
dc.subjectIntensive Careen_US
dc.subjectMortalityen_US
dc.subjectProtein/Albumin Ratioen_US
dc.subjectMortalityen_US
dc.subjectUniten_US
dc.titleC-reactive protein-to-serum albumin ratio as a marker of prognosis in adult intensive care populationen_US
dc.typeArticleen_US

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