C-reactive protein-to-serum albumin ratio as a marker of prognosis in adult intensive care population
Yükleniyor...
Dosyalar
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Aepress Sro
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
BACKGROUND: Patients in intensive care unit (ICU) require close follow up and clinical attention due to variability in the course of their underlying morbidities. The estimation of prognosis in these subjects has an utmost importance. Recent studies showed that C-reactive protein-to-serum albumin ratio (CAR) could be a reliable marker of inflammation in certain conditions. We aimed to compare CAR levels of deceased patients to those in survived subjects treated in ICU.PATIENTS AND METHODS: We retrospectively analyzed the data of adult patients. CAR was simply calculated by dividing the levels of CRP by those of serum albumin. Patients were grouped either as deceased or survived according to the prognosis. The data of the survived and deceased ICU subjects were compared.RESULTS: A total of 208 subjects, 101 deceased and 107 survived, were enrolled in the study. Median CAR levels of the deceased and survived subjects were 49.5 (3-153 %) and 11 (0.2-119 %), respectively (p < 0.001). CAR was significantly correlated with PDW (r = 0.24; p < 0.001) and serum creatinine (r = 0.27; p < 0.001) levels. In ROC analysis, CAR values higher than 30.2 % have 72 % sensitivity and 70 % specificity in predicting mortality in ICU population (AUC: 0.74; p < 0.001; 95% CI: 0.67-0.81).CONCLUSIONS: We suggest that CAR levels of the subjects in ICU should be evaluated during medical care. Increased CAR levels should alert physicians for a worse outcome in those subjects (Tab. 1, Fig. 1, Ref. 21). Text in PDF www.elis.sk
Açıklama
Anahtar Kelimeler
C-Reactive Protein-To-Serum Albumin Ratio, Intensive Care, Mortality, Protein/Albumin Ratio, Mortality, Unit
Kaynak
Bratislava Medical Journal-Bratislavske Lekarske Listy
WoS Q Değeri
Q2
Scopus Q Değeri
Q3
Cilt
124
Sayı
4
Künye
Karagoz, I., Ozer, B., Ital, I., Turkoglu, M., Disikirik, A., & PELTEK OZER, S. (2023). C-reactive protein-to-serum albumin ratio as a marker of prognosis in adult intensive care population. Bratislava Medical Journal/Bratislavske Lekarske Listy, 124(4).
