Salivary alpha amylase activity in migraine patients

dc.authorid0000-0002-1845-0902en_US
dc.authorid0000-0002-4060-3354en_US
dc.authorid0000-0002-9647-4432
dc.authorid0000-0002-5181-1773
dc.contributor.authorBuğdaycı, Güler
dc.contributor.authorYıldız, Serpil
dc.contributor.authorAltunrende, Burcu
dc.contributor.authorYıldız, Nebil
dc.contributor.authorAlkoy, Seval
dc.date.accessioned2021-06-23T19:26:56Z
dc.date.available2021-06-23T19:26:56Z
dc.date.issued2010
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: Salivary alpha amylase levels were measured to investigate sympathetic nervous system activity in migraine patients during attack, post-attack and interval periods of headache since salivary alpha amylase levels have been suggested as a potential indirect marker of sympatho-adrenal medullary activity in recent studies. Methods: 50 patients with migraine headache (13 patients in attack, 26 patients in post-attack and 11 patients in interval period) and 60 healthy volunteers were taken into the study. In all participants, the presence of anxiety was measured by using Hamilton Anxiety Rating scale. The visual analog scale scores for pain level estimation were obtained in the attack group. Results: The salivary alpha amylase levels were significantly lower in attack period (p < 0.01) and higher in post-attack period (p < 0.01) when compared with the control group. There was not any significant difference in salivary alpha amylase levels between interval period and control group (p > 0.05). There was a weak negative correlation between the salivary alpha amylase levels and the visual analog scale scores. Conclusions: This is the first study showing the dynamic nature of sympathetic nervous system activity by evaluating the salivary alpha amylase levels a noninvasive, reliable and an easy method in different periods of migraine headache. (C) 2010 Elsevier B.V. All rights reserved.en_US
dc.identifier.doi10.1016/j.autneu.2010.01.011
dc.identifier.endpage124en_US
dc.identifier.issn1566-0702
dc.identifier.issn1872-7484
dc.identifier.issue1-2en_US
dc.identifier.pmid20144881en_US
dc.identifier.scopus2-s2.0-77952546603en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage121en_US
dc.identifier.urihttps://doi.org/10.1016/j.autneu.2010.01.011
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6694
dc.identifier.volume155en_US
dc.identifier.wosWOS:000279043300020en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBuğdaycı, Güler
dc.institutionauthorYıldız, Serpil
dc.institutionauthorAltunrende, Burcu
dc.institutionauthorYıldız, Nebil
dc.institutionauthorAlköy, Seval
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofAutonomic Neuroscience-Basic & Clinicalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHeadacheen_US
dc.subjectMigraineen_US
dc.subjectSalivary Alpha Amylaseen_US
dc.subjectSympathetic Nervous Systemen_US
dc.titleSalivary alpha amylase activity in migraine patientsen_US
dc.typeArticleen_US

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