Phospholipase and proteinase activities in different Candida species isolated from anatomically distinct sites of healthy adults

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dc.authorid0000-0002-1964-424Xen_US
dc.authorid0000-0002-4893-5564
dc.authorid0000-0001-8165-1814
dc.authorid0000-0001-6203-5039
dc.authorid0000-0001-8224-8242
dc.authorid0000-0002-1736-9707
dc.contributor.authorÖksüz, Şükrü
dc.contributor.authorŞahin, İdris
dc.contributor.authorYıldırım, Mustafa
dc.contributor.authorGülcan, Aynur
dc.contributor.authorYavuz, Tevfik Mehmet
dc.contributor.authorKaya, Demet Ayşe
dc.contributor.authorKoç, Ayşe Nedret
dc.date.accessioned2021-06-23T19:19:56Z
dc.date.available2021-06-23T19:19:56Z
dc.date.issued2007
dc.departmentBAİBÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractThe aim of the present study was to determine in vitro phospholipase and protease activities in 122 Candida spp. isolated from several anatomically distinct sites of healthy adults. C. albicans (66.4%) was the most frequently isolated Candida spp. C. glabrata (7.3%), C. tropicalis (6.3%) and C. kefyr (4.9%) were the most frequently isolated non-C. albicans Candida spp. Fifty (40.9%) of the isolates examined were phospholipase positive and 64 (52.4%) were protease positive. Forty-three (53.8%) of the C. albicans isolates tested were phospholipase producers-however, only a few strains of non-C. albicans Candida spp. behaved in the same way. Protease activity was detected in 46 (56.7%) of the C. albicans strains tested and in a few strains of non-C. albicans Candida spp. The levels of phospholipase and protease activities in commensal isolates were found to be lower than the levels of other enzyme activities previously reported in clinical Candida spp. isolates. The phospholipase activity of Candida spp. was found to be higher in oral (59.0%) and fecal (42.8%) isolates. The protease activity of Candida spp. was found to be higher in urogenital (55.1%) and skin (58.8%) isolates. We conclude that further investigations will be needed on the phospholipase and protease activity of Candida spp. in healthy subjects in order to clarify their contribution to fungal virulence.en_US
dc.identifier.endpage283en_US
dc.identifier.issn1344-6304
dc.identifier.issn1884-2836
dc.identifier.issue5en_US
dc.identifier.pmid17881867en_US
dc.identifier.scopus2-s2.0-34948875353en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage280en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/6030
dc.identifier.urihttps://www.webofscience.com/wos/woscc/full-record/WOS:000249833600007
dc.identifier.volume60en_US
dc.identifier.wosWOS:000249833600007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYıldırım, Mustafa
dc.institutionauthorGülcan, Aynur
dc.institutionauthorYavuz, Tevfik
dc.institutionauthorKaya, Demet
dc.institutionauthorŞahin, İdris
dc.language.isoenen_US
dc.publisherNatl Inst Infectious Diseasesen_US
dc.relation.ispartofJapanese Journal Of Infectious Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPhospholipase and Proteinase Activitiesen_US
dc.subjectHealthy Adults
dc.titlePhospholipase and proteinase activities in different Candida species isolated from anatomically distinct sites of healthy adultsen_US
dc.typeArticleen_US

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