The condition of symmetrical sacroiliitis in axial spondyloarthritis: Comment on the article by Coates et al

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dc.authorid0000-0003-0290-9341en_US
dc.contributor.authorTönük, Şükrü Burak
dc.date.accessioned2023-05-24T08:15:42Z
dc.date.available2023-05-24T08:15:42Z
dc.date.issued2021en_US
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractTo the Editor:I read the article by Coates et al (1), recently published in Arthritis Care & Research, with great interest as it relates to the radiographic phenotype of axial spondyloarthritis according to the presence of HLA– B27, regardless of the primary diagno-sis of ankylosing spondylitis (AS) or psoriatic arthritis (PsA). The authors stated that the HLA– B27 gene is related to radiographic progression, syndesmophyte symmetry, and marginal syndes-mophytes, but not to sacroiliac symmetry. I would like to offer some suggestions from a biomechanical aspect, based on their important findings. Chronic biomechanical stress and microdam-age have been postulated as major triggering factors for lesion development, particularly in PsA. As compatible with a biome-chanical standpoint, tissue- specific kinetic factors (applied forces during motion) may play a critical role in the development of psori-atic lesions. Thus, PsA can de defined as an inflammatory disorder of more mobile musculoskeletal structures when AS is considered.en_US
dc.identifier.citationTönük, Ş. B. (2021). The condition of symmetrical sacroiliitis in axial spondyloarthritis: comment on the article by Coates et al. Arthritis Care & Research, 73(7), 1055-1056.en_US
dc.identifier.doi10.1002/acr.24359
dc.identifier.endpage1056en_US
dc.identifier.issn2151-464X
dc.identifier.issn2151-4658
dc.identifier.issue7en_US
dc.identifier.pmid32583976en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1055en_US
dc.identifier.urihttp://dx.doi.org/10.1002/acr.24359
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10940
dc.identifier.volume73en_US
dc.identifier.wosWOS:000661191200001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorTönük, Şükrü Burak
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofArthritis Care & Researchen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHLA– B27 Geneen_US
dc.subjectSacroiliac (SI)en_US
dc.subjectJointen_US
dc.titleThe condition of symmetrical sacroiliitis in axial spondyloarthritis: Comment on the article by Coates et alen_US
dc.typeLetteren_US

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