Atrial electrical and mechanical dysfunction in non-diabetic, nonhypertensive hemodialysis patients

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dc.authorid0000-0001-7306-5233en_US
dc.authorid0000-0002-4313-8478
dc.authorid0000-0001-8790-398X
dc.authorid0000-0002-5924-7476
dc.authorid0000-0002-4542-4064
dc.authorid0000-0001-5227-1716
dc.contributor.authorTekçe, Hikmet
dc.contributor.authorÖztürk, Serkan
dc.contributor.authorAktaş, Gülali
dc.contributor.authorTekçe, Buket Kın
dc.contributor.authorErdem, Alim
dc.contributor.authorÜyetürk, Uğur
dc.contributor.authorÖzyaşar, Mehmet
dc.contributor.authorDuman, Tuba Taslamacıoğlu
dc.contributor.authorYazıcı, Mehmet
dc.date.accessioned2021-06-23T19:36:47Z
dc.date.available2021-06-23T19:36:47Z
dc.date.issued2014
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractBackground: Abnormalities in atrial conduction times and mechanical functions are considered as independent predictors of atrial fibrillation. However, there is no data in literature about functional parameters and electromechanical delay intervals in nondiabetic, non-hypertensive hemodialysis (HD) patients. We aimed to study atrial electromechanical conduction times and mechanical functions in this population. Methods: Forty-two non-diabetic, normotensive hemodialysis patients and age and sex matched control subjects have been enrolled in the study. Standard and Tissue Doppler Echocardiography have been performed before mid-week dialysis session for HD group and on admission for control group. Results: PA(lateral,), PA(septum) durations of the hemodialysis group were significantly longer than control group (70.6 +/- 9.1 vs 55.3 +/- 2.7, 50.8 +/- 5.2 vs 44.4 +/- 2.1; p<0.01). Interatrial and left-right intraatrial electromechanical delay intervals were significantly longer in hemodialysis group compared to controls (31.6 +/- 7.2 vs 18.0 +/- 2.6, 19.8 +/- 7.9 vs 10.9 +/- 2.7, 11.8 +/- 5.1 vs 7.1 +/- 1.2, respectively; all p<0.01). Measurements of left atrial diameter, maximum, minimum and before atrial systole, volumes and passive-active emptying volumes were both elevated in hemodialysis group compared to controls (all p<0.01). Conclusions: This is the first study enlightening deterioration in atrial mechanical and electromechanical functions in nondiabetic, non-hypertensive HD population. Results of the present study reflect not only negative effects of structural remodeling, which has been mentioned in previous studies in literature, but also negative effects of electrical remodeling. Prolonged inter- and intra-atrial electromechanical delay intervals should be the underlying pathophysiological factors increasing the rate of atrial fibrillation in hemodialysis population.en_US
dc.identifier.endpage26en_US
dc.identifier.issn0393-6384
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84896874707en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage21en_US
dc.identifier.urihttps://www.actamedicamediterranea.com/archive/2014/medica-1/atrial-electrical-and-mechanical-dysfunction-in-non-diabetic-non-hypertensive-hemodialysis-patients/document
dc.identifier.urihttps://hdl.handle.net/20.500.12491/8055
dc.identifier.volume30en_US
dc.identifier.wosWOS:000335937700002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorTekçe, Hikmet
dc.institutionauthorÖztürk, Serkan
dc.institutionauthorAktaş, Gülali
dc.institutionauthorTekçe, Buket Kın
dc.institutionauthorErdem, Alim
dc.institutionauthorÜyetürk, Uğur
dc.institutionauthorÖzyaşar, Mehmet
dc.institutionauthorDuman, Tuba Taslamacıoğlu
dc.institutionauthorYazıcı, Mehmet
dc.language.isoenen_US
dc.publisherCarbone Editoreen_US
dc.relation.ispartofActa Medica Mediterraneaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAtrial Conduction Timeen_US
dc.subjectAtrial Fibrillationen_US
dc.subjectAtrial Mechanical Functionsen_US
dc.subjectAtrial Remodelingen_US
dc.subjectElectromechanical Delayen_US
dc.subjectHemodialysisen_US
dc.titleAtrial electrical and mechanical dysfunction in non-diabetic, nonhypertensive hemodialysis patientsen_US
dc.typeArticleen_US

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