In vitro stability of pregnancy-associated plasma protein A

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dc.authorid0000-0002-1273-0604
dc.authorid0000-0003-1937-9244
dc.contributor.authorCoşkun, Abdurrahman
dc.contributor.authorÖzdemir, İsmail
dc.contributor.authorYavuz, Özlem
dc.contributor.authorGüler, Selver
dc.contributor.authorŞahin, İbrahim E.
dc.date.accessioned2021-06-23T18:54:25Z
dc.date.available2021-06-23T18:54:25Z
dc.date.issued2005
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective: Pregnancy-associated plasma protein A is produced in high concentration by trophoblasts during pregnancy and maternal serum assessment between 11 and 14 weeks of gestation has significant utility in screening for Down syndrome and other chromosomal anomalies. We aimed to investigate the in vitro stability of pregnancy-associated plasma protein A. Materials and Methods: Blood samples were collected from volunteer pregnant women and divided into two groups. The first and second groups were stored at +2 to +8°C for 7 days and at -20°C for 28 days, respectively. Pregnancy-associated plasma protein A was determined each day in the first group and each week in the second group. Results: There was no statistically significant difference between measurements in each group (p>0.05). Conclusion: We concluded that serum pregnancy-associated plasma protein A is stable for at least 7 days at +2 to +8°C and 28 days at -20°C, and could be preserved for up to one month in average laboratory conditions.en_US
dc.identifier.endpage237en_US
dc.identifier.issn1309-0399
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-26944434690en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage235en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12491/4425
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-26944434690&partnerID=40&md5=1a1bd77d702f889ebc81bd5b620cb6b9
dc.identifier.volume6en_US
dc.identifier.wosWOS:000420562100009en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorCoşkun, Abdurrahman
dc.institutionauthorÖzdemir, İsmail
dc.institutionauthorYavuz, Özlem
dc.institutionauthorGüler, Selver
dc.institutionauthorŞahin, İbrahim E.
dc.language.isoenen_US
dc.relation.ispartofJournal of the Turkish German Gynecology Associationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDown syndromeen_US
dc.subjectIn vitroen_US
dc.subjectPregnancyen_US
dc.subjectPregnancy-associated plasma protein Aen_US
dc.subjectStabilityen_US
dc.titleIn vitro stability of pregnancy-associated plasma protein Aen_US
dc.typeArticleen_US

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