In vitro stability of pregnancy-associated plasma protein A
Yükleniyor...
Tarih
2005
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: Pregnancy-associated plasma protein A is produced in high concentration by trophoblasts during pregnancy and maternal serum assessment between 11 and 14 weeks of gestation has significant utility in screening for Down syndrome and other chromosomal anomalies. We aimed to investigate the in vitro stability of pregnancy-associated plasma protein A. Materials and Methods: Blood samples were collected from volunteer pregnant women and divided into two groups. The first and second groups were stored at +2 to +8°C for 7 days and at -20°C for 28 days, respectively. Pregnancy-associated plasma protein A was determined each day in the first group and each week in the second group. Results: There was no statistically significant difference between measurements in each group (p>0.05). Conclusion: We concluded that serum pregnancy-associated plasma protein A is stable for at least 7 days at +2 to +8°C and 28 days at -20°C, and could be preserved for up to one month in average laboratory conditions.
Açıklama
Anahtar Kelimeler
Down syndrome, In vitro, Pregnancy, Pregnancy-associated plasma protein A, Stability
Kaynak
Journal of the Turkish German Gynecology Association
WoS Q Değeri
N/A
Scopus Q Değeri
Q3
Cilt
6
Sayı
3
