Novel mortality markers for critically Ill patients

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dc.authorid0000-0002-9265-1008
dc.authorid0000-0003-2954-4784
dc.authorid0000-0001-5524-5767
dc.authorid0000-0003-4709-4705
dc.authorid0000-0002-2311-6431
dc.authorid0000-0002-9001-2309
dc.authorid0000-0001-7476-2217
dc.contributor.authorYoldaş, Hamit
dc.contributor.authorKaragöz, İbrahim
dc.contributor.authorÖgün, Muhammed Nur
dc.contributor.authorVelioğlu, Yusuf
dc.contributor.authorYıldız, İsa
dc.contributor.authorBilgi, Murat
dc.contributor.authorDemirhan, Abdullah
dc.date.accessioned2021-06-23T19:54:24Z
dc.date.available2021-06-23T19:54:24Z
dc.date.issued2020
dc.departmentBAİBÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.description.abstractAim: Inflammatory markers, such as the neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR), derived from a complete blood count have recently attracted attention as potential markers of morbidity and mortality in various diseases. The aim of the present study was to assess the usefulness of the NLR and PLR as markers of hospital stay and mortality of patients in intensive care units (ICUs). Methods: Patients treated in the ICU of our institution between October 2016 and August 2017 were enrolled in the study. After obtaining approval from the institutional committee, patient data were sourced from the institution's computerized database and retrospectively analyzed. The patients were assigned to 2 groups according to the outcomes: survivors and deceased. Results: The NLR of survivors and deceased patients was 2.06 (1.18-21.68) and 10.42 (2.85-48.2), respectively. The NLR was significantly elevated in deceased patients as compared with that of survivors (P < .001). Similarly, the median PLR of patients in the deceased group (268.9 [150-3000]) was significantly higher than that of patients in the survivor group (55.7 [11.8-152.5]). The difference in the PLR between groups was significant (P < .001). Conclusion: Both the NLR and PLR, as well as C-reactive protein, predicted mortality in this critically ill population. The PLR and NLR are easy-to-measure, inexpensive markers. Physicians should be aware of elevations in PLR and NLR in patient care in ICUs.en_US
dc.identifier.doi10.1177/0885066617753389
dc.identifier.endpage385en_US
dc.identifier.issn0885-0666
dc.identifier.issn1525-1489
dc.identifier.issue4en_US
dc.identifier.pmid29334832en_US
dc.identifier.scopus2-s2.0-85079337426en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage383en_US
dc.identifier.urihttps://doi.org/10.1177/0885066617753389
dc.identifier.urihttps://hdl.handle.net/20.500.12491/10532
dc.identifier.volume35en_US
dc.identifier.wosWOS:000513543000008en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorYoldaş, Hamit
dc.institutionauthorKaragöz, İbrahim
dc.institutionauthorÖgün, Muhammed Nur
dc.institutionauthorBilgi, Murat
dc.institutionauthorVelioğlu, Yusuf
dc.institutionauthorDemirhan, Abdullah
dc.institutionauthorYıldız, İsa
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofJournal Of Intensive Care Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIntensive Careen_US
dc.subjectInflammationen_US
dc.subjectMortalityen_US
dc.subjectPlatelet-to-lymphocyte Ratioen_US
dc.subjectNeutrophil-to-lymphocyte Ratioen_US
dc.titleNovel mortality markers for critically Ill patientsen_US
dc.typeArticleen_US

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