Pegylated interferon therapy during early pregnancy for hepatitis B infection: does it prevent vertical transmission?

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dc.authorid0000-0003-1685-0352en_US
dc.authorid0000-0003-0442-5981
dc.contributor.authorAtasoy, Halil İbrahim
dc.contributor.authorSırmatel, Pınar
dc.contributor.authorSırmatel, Fatma
dc.date.accessioned2021-06-23T19:48:58Z
dc.date.available2021-06-23T19:48:58Z
dc.date.issued2017
dc.departmentBAİBÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.description.abstractIn general, interferon (IFN) is avoided during pregnancy due to the possibility of fetal side effects. We, herein, reported two child-bearing women with chronic hepatitis B (HB) infection who used pegylated interferon alfa 2b (PEG IFN alpha 2b) in first trimester unintentionally. We compared HB contracting rates of gestations in which IFN was used and not used. The cases are unique in that they could highlight the importance of IFN use in early gestation for preventing vertical transmission particularly if combined with antiviral therapy for the rest of pregnancy.en_US
dc.identifier.doi10.1080/14767058.2016.1183639
dc.identifier.endpage747en_US
dc.identifier.issn1476-7058
dc.identifier.issn1476-4954
dc.identifier.issue6en_US
dc.identifier.pmid27125766en_US
dc.identifier.scopus2-s2.0-84969677189en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage745en_US
dc.identifier.urihttps://doi.org/10.1080/14767058.2016.1183639
dc.identifier.urihttps://hdl.handle.net/20.500.12491/9293
dc.identifier.volume30en_US
dc.identifier.wosWOS:000393297500021en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAtasoy, Halil İbrahim
dc.institutionauthorSırmatel, Fatma
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal Of Maternal-Fetal & Neonatal Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHepatitis Ben_US
dc.subjectInfectionen_US
dc.subjectPeginterferon Alfa 2ben_US
dc.subjectPregnancy Outcomeen_US
dc.titlePegylated interferon therapy during early pregnancy for hepatitis B infection: does it prevent vertical transmission?en_US
dc.typeArticleen_US

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