Pegylated interferon therapy during early pregnancy for hepatitis B infection: does it prevent vertical transmission?
Yükleniyor...
Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor & Francis Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In general, interferon (IFN) is avoided during pregnancy due to the possibility of fetal side effects. We, herein, reported two child-bearing women with chronic hepatitis B (HB) infection who used pegylated interferon alfa 2b (PEG IFN alpha 2b) in first trimester unintentionally. We compared HB contracting rates of gestations in which IFN was used and not used. The cases are unique in that they could highlight the importance of IFN use in early gestation for preventing vertical transmission particularly if combined with antiviral therapy for the rest of pregnancy.
Açıklama
Anahtar Kelimeler
Hepatitis B, Infection, Peginterferon Alfa 2b, Pregnancy Outcome
Kaynak
Journal Of Maternal-Fetal & Neonatal Medicine
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
30
Sayı
6
